ReviewPharmaceutics2022
Drug Stability: ICH versus Accelerated Predictive Stability Studies.
Review in Pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
70 citing papers in PubMed.
- Common Deficiencies in Dossiers of Finished Pharmaceutical Products Submitted for Registration and Related Factors: A Mixed-Method Study in Tanzania.Therapeutic innovation & regulatory science · 2026Article
- Comprehensive Stability Assessment of Squalene in a Nanoemulsion Adjuvant and the SpiN-Tec Vaccine: HPLC Quantification, Stress Testing, and Stability Studies.AAPS PharmSciTech · 2026Article
- Formulation and Box-Behnken optimization of roflumilast loaded ultradeformable nanotransethosomal gel: physicochemical characterization, stability, dermal permeation, and antipsoriatic efficacy in an imiquimod-induced psoriasis model.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Development and Optimization of Puerarin-loaded Proniosomal gel for topical ocular delivery: an in vitro and ex vivo evaluation.International ophthalmology · 2026Article
- Analgesic and anti-inflammatory activities of Vitex trifolia extract and development of a topical herbal cream.Journal of Ayurveda and integrative medicine · 2026Article
- Dual Anticancer and Antibacterial Applications of Active Particle Aggregates Containing Metal Phthalocyanines in Dark.International journal of molecular sciences · 2026Article
- Preclinical investigation of hydroxychloroquine loaded ethosomal gel for topical treatment of rheumatoid arthritis.Inflammopharmacology · 2026Article
- Development of a crocetin-glycyrrhizic acid supramolecular composite pigment for enhancing meat color and reducing contaminant formation during heat processin.Food chemistry: X · 2026Article
- Anti-acne cinnamic acid bigel: a hybrid topical system for concurrent modulation of inflammation and microbial load.Inflammopharmacology · 2026Article
- Nutritional detoxification strategies in aquaculture: bioactive feed additives mitigating oxidative stress and xenobiotic toxicity in fish.Fish physiology and biochemistry · 2026Review
- Rational Design and Efficacy Evaluation of a Novel Solid Dispersion-Based Bempedoic Acid-Ezetimibe Fixed-Dose Combination Tablet Versus NexlizetPharmaceutics · 2026Article
- Potential of Time Domain Nuclear Magnetic Resonance as a Noninvasive Method for Detection and Quantification of Protein Glycation in Biopharmaceuticals.Analytical chemistry · 2026Article
- Development and optimization of asiaticoside co-crystal-loaded transdermal patch for topical therapy.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Nanoemulgels as Advanced Topical Drug Delivery Systems: Mechanistic Insights and Therapeutic Applications in Skin Disorders, Infections, Wound Healing, and Cancer.Pharmaceuticals (Basel, Switzerland) · 2026Review
- A newly developed rapid K39-based LeishmaCHECK Ab ELISA for high-throughput serological screening of canine leishmaniasis.Current research in parasitology & vector-borne diseases · 2026Article
- Development of a 50% (w/v) aluminium chloride hexahydrate solution as haemostatic agent.European journal of hospital pharmacy : science and practice · 2025Article
- Stability study of topotecan in ophthalmic prefilled syringes for intravitreal delivery.European journal of hospital pharmacy : science and practice · 2025Article
- Novel ethosomal gel formulation for enhanced transdermal delivery of curcumin and cyclosporine: a preclinical approach to rheumatoid arthritis management.Drug delivery · 2025Article
- Crystal engineering optimizes emodin-tetramethylpyrazine combination: From cocrystal design toInternational journal of pharmaceutics: X · 2025Article
- Understanding the Impact of Sustainable Pharmaceutical Packaging on the Chemical Stability of Silodosin.Pharmaceutics · 2025Article
10 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
The International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH), along with the World Health Organization (WHO), has provided a set of guidelines (ICH Q1A-E, Q3A-B, Q5C, Q6A-B) intended to unify the standards for the European Union, Japan, and the United States to facilitate the mutual acceptance of stability data that are sufficient for registration by the regulatory authorities in these jurisdictions. Overall, ICH stability studies involve a drug substance tested under storage conditions and assess its thermal stability and sensitivity to moisture. The long-term testing should be performed over a minimum of 12 months at 25 °C ± 2 °C/60%
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.