Evidence map›Paper›PMID 36365140›Full record

ArticlePharmaceutics2022

Investigation of a Minocycline-Loaded Nanoemulgel for the Treatment of Acne Rosacea.

Ayesha Siddiqui, Pooja Jain, Thompson Santosh Alex, Mohammed Asgar Ali, Nazia Hassan, Jamshed Haneef, Punnoth Poonkuzhi Naseef, Mohamed Saheer Kuruniyan, Mohd Aamir Mirza, Zeenat Iqbal

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Ayesha SiddiquiDepartment of Pharmaceutics, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi 110062, India.
Pooja JainDepartment of Pharmaceutics, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi 110062, India.ORCID 0000-0002-7991-6956
Thompson Santosh AlexDepartment of Pharmaceutics, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi 110062, India.
Mohammed Asgar AliDepartment of Pharmaceutics, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi 110062, India.ORCID 0000-0001-5476-3108
Nazia HassanDepartment of Pharmaceutics, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi 110062, India.
Jamshed HaneefDepartment of Pharmaceutical Chemistry, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi 110062, India.
Punnoth Poonkuzhi NaseefDepartment of Pharmaceutics, Moulana College of Pharmacy, Perinthalmanna 679321, India.ORCID 0000-0001-9692-6323
Mohamed Saheer KuruniyanDepartment of Dental Technology, College of Applied Medical Sciences, King Khalid University, Abha 61421, Saudi Arabia.ORCID 0000-0003-3341-0914
Mohd Aamir MirzaDepartment of Pharmaceutics, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi 110062, India.ORCID 0000-0002-5780-7601
Zeenat IqbalDepartment of Pharmaceutics, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi 110062, India.
Jamia Hamdard · INKing Khalid University · SAMoulana Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the present investigation, a nanoemulgel of minocycline was formulated and optimized for an improved drug delivery and longer retention time in the targeted area. Combining eucalyptus oil, Tween 20, and Transcutol HP, different o/w nanoemulsions were formulated by the oil phase titration method and optimized by pseudo-ternary phase diagrams. The morphology, droplet size, viscosity, and refractive index of the thermodynamically stable nanoemulsion were determined. Furthermore, optimized nanoemulsion was suspended in 1.0%

Indexed as

Carbopol 940eucalyptus oilminocyclineo/w nanoemulsionpermeation study

Identifiers

PMID36365140
PMCPMC9692270
OpenAlexW4307943821

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.