Evidence map›Paper›PMID 36365111›Full record

ArticlePharmaceutics2022

Magnetite Microspheres for the Controlled Release of Rosmarinic Acid.

Cristina Chircov, Diana-Cristina Pîrvulescu, Alexandra Cătălina Bîrcă, Ecaterina Andronescu, Alexandru Mihai Grumezescu

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Zinc/Cerium-Substituted Magnetite Nanoparticles for Biomedical Applications.International journal of molecular sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Cristina ChircovDepartment of Science and Engineering of Oxide Materials and Nanomaterials, University Politehnica of Bucharest, 011061 Bucharest, Romania.ORCID 0000-0002-8695-6884
Diana-Cristina PîrvulescuFaculty of Medical Engineering, University Politehnica of Bucharest, 060042 Bucharest, Romania.
Alexandra Cătălina BîrcăDepartment of Science and Engineering of Oxide Materials and Nanomaterials, University Politehnica of Bucharest, 011061 Bucharest, Romania.
Ecaterina AndronescuDepartment of Science and Engineering of Oxide Materials and Nanomaterials, University Politehnica of Bucharest, 011061 Bucharest, Romania.ORCID 0000-0002-2226-5849
Alexandru Mihai GrumezescuDepartment of Science and Engineering of Oxide Materials and Nanomaterials, University Politehnica of Bucharest, 011061 Bucharest, Romania.ORCID 0000-0003-3036-094X
Universitatea Națională de Știință și Tehnologie Politehnica București · ROAcademia Oamenilor de Știință din România · ROUniversity of Bucharest · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since cancer incidence is constantly increasing, novel and more efficient treatment methods that overcome the current limitations of chemotherapy are continuously explored. In this context, the aim of the present study was to investigate the potential of two types of magnetite microspheres as drug delivery vehicles for the controlled release of rosmarinic acid (RA) in anticancer therapies. The magnetite microspheres were obtained through the solvothermal method by using polyethylene glycol (PEG) with two different molecular weights as the surfactant. The physicochemical characterization of the so-obtained drug delivery carriers involved X-ray diffraction (XRD) coupled with Rietveld refinement, scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FT-IR), dynamic light scattering (DLS) and zeta potential, and UV-Vis spectrophotometry. The magnetite-based anticancer agents were biologically evaluated through the ROS-Glo H

Indexed as

anticancermagnetitenatural biocompoundspolyethylene glycolpolyphenolsrosmarinic acid

Identifiers

PMID36365111
PMCPMC9693273
OpenAlexW4307551833

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.