Evidence map›Paper›PMID 36365100›Full record

ArticlePharmaceutics2022

The Improved Brain-Targeted Drug Delivery of Edaravone Temperature-Sensitive Gels by Ultrasound for γ-ray Radiation-Induced Brain Injury.

Qian Li, Yizhi Zhang, Jinglu Hu, Bochuan Yuan, Pengcheng Zhang, Yaxin Wang, Xu Jin, Lina Du, Yiguang Jin

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Qian LiSchool of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, China.
Yizhi ZhangSchool of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, China.
Jinglu HuDepartment of Pharmaceutical Sciences, Beijing Institute of Radiation Medicine, Beijing 100850, China.
Bochuan YuanDepartment of Pharmaceutical Sciences, Beijing Institute of Radiation Medicine, Beijing 100850, China.
Pengcheng ZhangBeijing Tiantan Hospital, Capital Medical University, Beijing 100070, China.
Yaxin WangBeijing Tiantan Hospital, Capital Medical University, Beijing 100070, China.
Xu JinBeijing Tiantan Hospital, Capital Medical University, Beijing 100070, China.
Lina DuSchool of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, China.ORCID 0000-0001-8103-5974
Yiguang JinDepartment of Pharmaceutical Sciences, Beijing Institute of Radiation Medicine, Beijing 100850, China.ORCID 0000-0002-3528-1397
Capital Medical University · CNShandong University of Traditional Chinese Medicine · CNHenan University · CN

Funding

Beijing Natural Science Foundation 7202147
6 · The paper itself

Abstract

Radiation-induced brain injury (RBI) is a common neurological disease caused by ionizing radiation (IR). Edaravone (EDA) is a free radical scavenger, has the potential to treat RBI. EDA loaded temperature-sensitive gels (TSGs) were prepared for subcutaneous injection to improve inconvenient administration of intravenous infusion. RBI mice model was established by irradiation of

Indexed as

behavior testsedaravoneradiation-induced brain injurytemperature-sensitive gelsultrasound

Identifiers

PMID36365100
PMCPMC9698875
OpenAlexW4307547401

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.