Evidence map›Paper›PMID 36365097›Full record

ArticlePharmaceutics2022

Resveratrol/Hydrazone Hybrids: Synthesis and Chemopreventive Activity against Colorectal Cancer Cells.

Wilson Castrillón-López, Angie Herrera-Ramírez, Gustavo Moreno-Quintero, Juan Carlos Coa, Tonny W Naranjo, Wilson Cardona-Galeano

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Potentials of N-Acyl Hydrazones Against Colorectal Cancer: A Mini Review.Anti-cancer agents in medicinal chemistry · 2025
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Wilson Castrillón-LópezChemistry of Colombian Plants Group, Institute of Chemistry, Faculty of Exact and Natural Sciences, University of Antioquia, Medellín 050010, Colombia.
Angie Herrera-RamírezChemistry of Colombian Plants Group, Institute of Chemistry, Faculty of Exact and Natural Sciences, University of Antioquia, Medellín 050010, Colombia.ORCID 0000-0003-2462-0143
Gustavo Moreno-QuinteroChemistry of Colombian Plants Group, Institute of Chemistry, Faculty of Exact and Natural Sciences, University of Antioquia, Medellín 050010, Colombia.
Juan Carlos CoaChemistry of Colombian Plants Group, Institute of Chemistry, Faculty of Exact and Natural Sciences, University of Antioquia, Medellín 050010, Colombia.
Tonny W NaranjoMedical and Experimental Mycology Group, Corporación para Investigaciones Biológicas, Medellín 050034, Colombia.ORCID 0000-0003-4667-6391
Wilson Cardona-GaleanoChemistry of Colombian Plants Group, Institute of Chemistry, Faculty of Exact and Natural Sciences, University of Antioquia, Medellín 050010, Colombia.ORCID 0000-0002-5374-1211
Universidad de Antioquia · COUniversidad Pontificia Bolivariana · CO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A series of resveratrol/hydrazone hybrids were obtained and elucidated by spectroscopic analysis. All compounds were evaluated against colorectal cancer cells (SW480 and Sw620) and nonmalignant cell lines (HaCaT and CHO-K1) to establish the selectivity index. Among the hybrids evaluated, compounds

Indexed as

antiproliferative activityapoptosiscolorectal cancercytotoxicityhybrid compoundshydrazonemitochondrial depolarizationresveratrol

Identifiers

PMID36365097
PMCPMC9694494
OpenAlexW4307189021

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.