Evidence map›Paper›PMID 36365009›Full record

ReviewPathogens (Basel, Switzerland)2022

Preventive Treatment for Household Contacts of Drug-Susceptible Tuberculosis Patients.

Nicole Salazar-Austin, Christiaan Mulder, Graeme Hoddinott, Theresa Ryckman, Colleen F Hanrahan, Kavindhran Velen, Lucy Chimoyi, Salome Charalambous, Violet N Chihota

Open access · goldAbstract readReview
In one paragraph

Review in Pathogens (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
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  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 4 countries.

Nicole Salazar-AustinDepartment of Pediatrics, Johns Hopkins University, Baltimore, MD 21287, USA.ORCID 0000-0002-9875-9319
Christiaan MulderDepartment of TB Elimination and Health System Innovations, KNCV Tuberculosis Foundation, 2516 The Hague, The Netherlands.
Graeme HoddinottDesmond Tutu TB Centre, Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town 7500, South Africa.ORCID 0000-0001-5915-8126
Theresa RyckmanDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21287, USA.
Colleen F HanrahanDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21287, USA.ORCID 0000-0002-4544-4591
Kavindhran VelenFaculty of Medicine and Health, The Central Clinical School, The University of Sydney, 90-92 Parramatta Road, Sydney, NSW 2006, Australia.ORCID 0000-0001-8577-3915
Lucy ChimoyiThe Aurum Institute, Parktown, Johannesburg 2000, South Africa.
Salome CharalambousThe Aurum Institute, Parktown, Johannesburg 2000, South Africa.
Violet N ChihotaThe Aurum Institute, Parktown, Johannesburg 2000, South Africa.ORCID 0000-0003-1444-9266
Johns Hopkins University · USUniversity of the Witwatersrand · ZAAurum Institute · ZADesmond Tutu HIV Foundation · ZAThe University of Sydney · AUTuBerculosis Vaccine Initiative · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

People who live in the household of someone with infectious pulmonary tuberculosis are at a high risk of tuberculosis infection and subsequent progression to tuberculosis disease. These individuals are prioritized for contact investigation and tuberculosis preventive treatment (TPT). The treatment of TB infection is critical to prevent the progression of infection to disease and is prioritized in household contacts. Despite the availability of TPT, uptake in household contacts is poor. Multiple barriers prevent the optimal implementation of these policies. This manuscript lays out potential next steps for closing the policy-to-implementation gap in household contacts of all ages.

Indexed as

household contactsTB infectionTB preventive treatment

Identifiers

PMID36365009
PMCPMC9696065
OpenAlexW4308122646

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.