Evidence map›Paper›PMID 36364994›Full record

ReviewPathogens (Basel, Switzerland)2022

The Continuum of Microbial Ecosystems along the Female Reproductive Tract: Implications for Health and Fertility.

Claudia Nakama, Brice Thompson, Cory Szybala, Andrea McBeth, Piper Dobner, Heather Zwickey

Open access · goldAbstract readReview
In one paragraph

Review in Pathogens (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. All Properties of Infertility Microbiome in a Review Article.Journal of clinical laboratory analysis · 2025
    Review
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Claudia NakamaHelfgott Research Institute, National University of Natural Medicine, Portland, OR 97201, USA.
Brice ThompsonHelfgott Research Institute, National University of Natural Medicine, Portland, OR 97201, USA.
Cory SzybalaThaena, Inc., Vancouver, WA 98661, USA.
Andrea McBethHelfgott Research Institute, National University of Natural Medicine, Portland, OR 97201, USA.
Piper DobnerThaena, Inc., Vancouver, WA 98661, USA.
Heather ZwickeyHelfgott Research Institute, National University of Natural Medicine, Portland, OR 97201, USA.ORCID 0000-0002-1600-401X
National University of Natural Medicine · US

Funding

Thaena, Inc. N/A
6 · The paper itself

Abstract

The microbial ecosystem of the female urogenital tract is composed of many niche microenvironments across multiple organ systems in the urinary and reproductive tract. It is complex and contains a variety of bacteria, archaea, viruses, yeast, and protozoa-Many of which are still unidentified or whose functionality is unknown. Unlike the gut microbiome, whose composition is relatively stable in the absence of external perturbations, the urogenital microbiome is constantly shifting in response to biological cycles such as hormonal fluctuations during menstruation. Microbial composition differs between women but the dominance of some microbial families, such as

Indexed as

bacterial vaginosisdysbiosislactic acidLactobacillusmetabolomicsreproductive immunityunexplained infertilityurogenital microbiomevaginal community state types

Identifiers

PMID36364994
PMCPMC9693519
OpenAlexW4307705779

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.