Evidence map›Paper›PMID 36364940›Full record

ArticleNutrients2022

An In Silico Framework to Mine Bioactive Peptides from Annotated Proteomes: A Case Study on Pancreatic Alpha Amylase Inhibitory Peptides from Algae and Cyanobacteria.

Lorenzo Pedroni, Florinda Perugino, Gianni Galaverna, Chiara Dall'Asta, Luca Dellafiora

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. MicroalgaFoods (Basel, Switzerland) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Lorenzo PedroniDepartment of Food and Drug, University of Parma, 43124 Parma, Italy.ORCID 0000-0003-3666-2631
Florinda PeruginoDepartment of Food and Drug, University of Parma, 43124 Parma, Italy.ORCID 0000-0001-8789-5158
Gianni GalavernaDepartment of Food and Drug, University of Parma, 43124 Parma, Italy.ORCID 0000-0001-9042-2378
Chiara Dall'AstaDepartment of Food and Drug, University of Parma, 43124 Parma, Italy.ORCID 0000-0003-0716-8394
Luca DellafioraDepartment of Food and Drug, University of Parma, 43124 Parma, Italy.ORCID 0000-0002-1901-3317
University of Parma · IT

Funding

Regione Emilia Romagna (Italy) This research was partially funded by the Emilia-Romagna Region (Italy) within the context of "BIG DATA per una regione europea più ecologica, digitale e resiliente" (Deliberazione della G.R. n. 752 del 24/05/2021; Rif. PA 2021-15857/RER).
6 · The paper itself

Abstract

Bioactive peptides may exert beneficial activities in living organisms such as the regulation of glucose metabolism through the inhibition of alpha amylases. Algae and cyanobacteria are gaining a growing interest for their health-promoting properties, and possible effects on glucose metabolism have been described, although the underlying mechanisms need clarification. This study proposes a computer-driven workflow for a proteome-wide mining of alpha amylase inhibitory peptides from the proteome of

Indexed as

Chlorella vulgarisCyanobacteriaalpha-AmylasesGlucosePancreatic alpha-AmylasesPeptidesProteomealpha-AmylasesGlucosePancreatic alpha-AmylasesPeptidesProteomeanti-nutrientsbioactive peptidesbioinformaticsin silico digestionmolecular modelingpancreatic alpha amylase inhibitors

Identifiers

PMID36364940
PMCPMC9658718
OpenAlexW4308720234

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.