Evidence map›Paper›PMID 36364907›Full record

Trial reportNutrients2022

Effects of

Rujira Nonsa-Ard, Ploypailin Aneknan, Terdthai Tong-Un, Sittisak Honsawek, Naruemon Leelayuwat

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Rujira Nonsa-ArdBiomedical Sciences Program, Graduate School, Khon Kaen University, Khon Kaen 40002, Thailand.
Ploypailin AneknanExercise and Sport Sciences Development and Research Group, Khon Kaen University, Khon Kaen 40002, Thailand.
Terdthai Tong-UnDepartment of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.ORCID 0000-0002-5286-0788
Sittisak HonsawekCenter of Excellence in Osteoarthritis and Musculoskeleton, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand.ORCID 0000-0003-3852-9092
Naruemon LeelayuwatGraduate School, Khon Kaen University, Khon Kaen 40002, Thailand.
Khon Kaen University · THChulalongkorn University · TH

Funding

Enhancing Youth Violence Prevention in Urban CommunitiesK24HD052559 · NICHD · JOHNS HOPKINS UNIVERSITY · PI CHENG, TINA LEE · 2007 to 2011
$855k
Blackmores Limited and Exercise and Sport Sciences Development and Research Group, Khon Kaen University, Khon Kaen, Thailand. N/ANICHD NIH HHS K24 HD052559
6 · The paper itself

Abstract

We investigated the effects of Irvingia gabonensis (IG) kernel extract on the metabolism, adiposity indices, redox status, inflammation, adipocytokines, blood leukocyte relative telomere length (RTL), and aerobic capacity of overweight/obese individuals. All participants used the first 12-week phase to monitor body weight. They were then randomly divided into two groups: (1) 300 mg IG or (2) placebo (PLA). Both groups took one tablet per day for 12 weeks. The variables were measured before supplementation and after 3, 6, and 12 weeks of supplementation. RTL and aerobic capacity were measured before and after 12 weeks. Compared with the PLA, the IG increased plasma vitamin C after supplementation at 6 (p < 0.01) and 12 weeks (p < 0.05) and serum adiponectin after 3 weeks (p < 0.05). Compared with before supplementation, plasma malondialdehyde in the IG and serum leptin in the PLA were decreased after 12-week supplementation, without any differences between the groups. There were no differences between groups with respect to metabolism, inflammation, RTL, and aerobic capacity after the supplementation. We suggest that 12-week daily IG supplementation improved plasma vitamin C and adiponectin. The findings show the possible mechanism contributing to the effect of IG supplementation on a reduction in obesity-related complications.

Indexed as

AntioxidantsOverweightAdipokinesAdiponectinAscorbic AcidCelluloseDietary SupplementsDouble-Blind MethodHumansInflammationObesityPlant ExtractsPolyestersTelomereAdipokinesAdiponectinAntioxidantsAscorbic AcidCellulosedikanutPlant ExtractsPolyestersadiponectinascorbic acidbiomarker of agingbody mass indexIrvingia gabonensismalondialdehydemaximum oxygen consumptionsubstrate utilization

Identifiers

PMID36364907
PMCPMC9656030
OpenAlexW4308334884

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.