Evidence map›Paper›PMID 36364884›Full record

Trial reportNutrients2022

Bioactive Yoghurt Containing Curcumin and Chlorogenic Acid Reduces Inflammation in Postmenopausal Women.

Noha Ahmed Nasef, Rohith N Thota, Anthony N Mutukumira, Kay Rutherfurd-Markwick, Martin Dickens, Pramod Gopal, Harjinder Singh, Manohar L Garg

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 3 pooled it
0.7field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 3 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Noha Ahmed NasefRiddet Research Institute, Massey University, Palmerston North 4442, New Zealand.ORCID 0000-0001-6212-5026
Rohith N ThotaMacquarie Medical School, Macquarie University, North Ryde, NSW 2109, Australia.
Anthony N MutukumiraSchool of Food and Advanced Technology, College of Science, Massey University, Auckland 0745, New Zealand.
Kay Rutherfurd-MarkwickSchool of Health Sciences, College of Health, Massey University, Auckland 0745, New Zealand.ORCID 0000-0002-8815-3786
Martin DickensSchool of Health Sciences, College of Health, Massey University, Auckland 0745, New Zealand.ORCID 0000-0002-7605-3964
Pramod GopalRiddet Research Institute, Massey University, Palmerston North 4442, New Zealand.ORCID 0000-0002-3434-5555
Harjinder SinghRiddet Research Institute, Massey University, Palmerston North 4442, New Zealand.
Manohar L GargRiddet Research Institute, Massey University, Palmerston North 4442, New Zealand.ORCID 0000-0003-0514-0865
Massey University · NZPlant & Food Research · NZUniversity of Newcastle Australia · AU

Funding

Tertiary Education Commission NA
6 · The paper itself

Abstract

Menopause is marked by a gradual and permanent decrease of estrogen from the ovaries, leading to metabolic and physiological changes in the body. Combined with increased body mass index, postmenopausal women have elevated systemic inflammation and metabolic disturbances leading to increased risk of developing chronic diseases. A bioactive coconut yoghurt containing curcumin and chlorogenic acid was developed with the potential to target inflammatory processes. In this randomized crossover study, healthy postmenopausal women with a BMI of 25-40 were recruited to consume 125 g of either the bioactive or placebo yoghurt. Blood samples were collected at baseline, 30 min, and 1, 2, 3 and 4 h postprandially. Plasma inflammatory markers (TNFα and IL6) and metabolic markers (triglycerides, insulin and glucose) were measured. Participants had significantly lower plasma TNFα C

Indexed as

CurcuminYogurtChlorogenic AcidCross-Over StudiesFemaleHumansInflammationPostmenopauseTumor Necrosis Factor-alphaChlorogenic AcidCurcuminTumor Necrosis Factor-alphachlorogenic acidcurcuminfunctional foodinflammationmenopauseyoghurt

Identifiers

PMID36364884
PMCPMC9657450
OpenAlexW4309089940

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.