Observational studyNutrients2022
Diagnostic Utility of Temporal Muscle Thickness as a Monitoring Tool for Muscle Wasting in Neurocritical Care.
Observational study in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Retrospective analysis of temporalis muscle thickness as a biomarker of functional level in adults with cerebral palsy.Journal of pediatric rehabilitation medicine · 2026Article
- Intensive Care Unit Acquired Weakness as a Modifiable Organ Dysfunction? A Narrative Review of Evolving Diagnostic and Therapeutic Concepts.Nutrients · 2026Review
- Soft tissue changes in Dementia: A comprehensive systematic review.Aging brain · 2026Review
- Predictive value of changes in temporal muscle volume for 6-month functional outcome in patients with hypertensive intracerebral hemorrhage.Frontiers in neurology · 2026Article
- Temporal fossa radio- and sonoanatomy revisited: a multimodal approach to standardizing temporalis muscle thickness measurement.Journal of ultrasound · 2025Review
- Temporalis muscle thickness correlates with premorbid frailty in patients resuscitated from cardiac arrest.Resuscitation · 2025Article
- Age- and sex-adjusted CT-based reference values for temporal muscle thickness, cross-sectional area and radiodensity.Scientific reports · 2025Article
- Methodologies and clinical applications of lower limb muscle ultrasound in critically ill patients: a systematic review and meta-analysis.Annals of intensive care · 2024Review
- Accelerometer-derived movement features as predictive biomarkers for muscle atrophy in neurocritical care: a prospective cohort study.Critical care (London, England) · 2024Observational
- Reduced temporal muscle thickness predicts shorter survival in patients undergoing chronic subdural haematoma drainage.Journal of cachexia, sarcopenia and muscle · 2024Article
- Changes in temporal muscle dimensions and their clinical impact in out-of-hospital cardiac arrest survivors.Resuscitation plus · 2024Article
- Association between the Thickness or Area of the Temporal Muscle and Skeletal Muscle Mass in Bioimpedance Analysis.Gerontology · 2024Article
- Update on Lean Body Mass Diagnostic Assessment in Critical Illness.Diagnostics (Basel, Switzerland) · 2023Review
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Temporalis muscle (TM) atrophy has emerged as a potential biomarker for muscle wasting. However, its diagnostic utility as a monitoring tool in intensive care remains uncertain. Hence, the objective of this study was to evaluate the diagnostic value of sequential ultrasound- and computed tomography (CT)-based measurements of TM thickness (TMT). With a prospective observational design, we included 40 patients without preexisting sarcopenia admitted to a neurointensive care unit. TMT measurements, performed upon admission and serially every 3−4 days, were correlated with rectus femoris muscle thickness (RFT) ultrasound measurements. Interrater reliability was assessed by Bland Altmann plots and intraclass correlation coefficient (ICC). Analysis of variance was performed in subgroups to evaluate differences in the standard error of measurement (SEM). RFT decline was paralleled by ultrasound- as well as CT-based TMT measurements (TMT to RFT: r = 0.746, p < 0.001; CT-based TMT to ultrasound-based RFT: r = 0.609, p < 0.001). ICC was 0.80 [95% CI 0.74, 0.84] for ultrasound-based assessment and 0.90 [95% CI 0.88, 0.92] for CT-based TMT measurements. Analysis of variance for BMI, Heckmatt score, fluid balance, and agitation showed no evidence of measurement errors in these subgroups. This study demonstrates the clinical feasibility and utility of ultrasound- and CT-based TMT measurements for the assessment of muscle wasting.
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