ReviewNutrients2022
Parenteral Nutrition Overview.
Review in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
73 citing papers in PubMed, 6 syntheses or guidelines pooled it, 128 citations in OpenAlex.
- A Clinical Practice Update for the Management of Patients With Disorders of Gut-Brain Interaction and Altered Food Intake Behavior.Neurogastroenterology and motility · 2026Guideline
- Pooled it
- Efficacy and Safety of a Combination of Enteral and Parenteral Nutrition Support in the Postoperative Period for Patients with Gastrointestinal Cancer: A Systematic Review and Meta-Analysis.Balkan medical journal · 2025Pooled it
- Best evidence summary for the rational use of parenteral nutrition in hospitalized cancer patients.Frontiers in nutrition · 2025Pooled it
- Outcomes for Patients Receiving Multi-Chamber Bags for the Delivery of Parenteral Nutrition: A Systematic Review.Nutrients · 2024Pooled it
- Risk Factors for Gallstones in Crohn's Disease: A Systematic Review and Meta-Analysis.Digestive diseases and sciences · 2024Pooled it
- Evaluation of safe utilization of L-threonine for supplementation in healthy adults: a randomized double blind controlled trial.Amino acids · 2025Trial
- Trial
- Parenteral nutrition and hospital outcomes in Australian adults: A descriptive cohort study.JPEN. Journal of parenteral and enteral nutrition · 2026Article
- An International Expert Consensus Statement and Guidance Document on Implementation of Nutritional Supplementation in Patients on Dialysis.Kidney international reports · 2026Article
- Analysis of factors driving variations in neonatal parenteral nutrition over a decade: A retrospective study.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2026Article
- Observational
- Parenteral dextrose during refeeding is associated with electrolyte deficiencies in anorexia nervosa: a route-specific analysis of oral and parenteral nutrition.Journal of eating disorders · 2026Article
- Bridging the Gap in the Clinical Application of Advanced Parenteral Nutrition Formulations: From Efficacy to Real-World Challenges.Advances in nutrition (Bethesda, Md.) · 2026Review
- Patterns of parenteral nutrition use in the inpatient setting: A retrospective cohort study.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2026Article
- Early versus late supplemental parenteral nutrition in gastrointestinal cancer patients undergoing major abdominal surgery: 5-year outcomes from a randomized clinical trial.International journal of surgery (London, England) · 2026Article
- Optimizing Perioperative Nutrition in Elective Gastrointestinal Surgery: An ERAS-Focused Narrative Review.Nutrients · 2026Review
- Artificial Intelligence in Parenteral Nutrition: Enhancing Patient Outcomes Through Global Experience and the Bulgarian Context.Nutrients · 2026Review
- Evaluating a Clinical Decision Support System for Optimizing Total Parenteral Nutrition in Adult Oncology Patients.Nutrients · 2026Article
- Dual-energy CT liver fat fraction as prognostic imaging biomarker in critically ill patients.European radiology · 2026Article
13 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Parenteral nutrition (PN) is a life-saving intervention for patients where oral or enteral nutrition (EN) cannot be achieved or is not acceptable. The essential components of PN are carbohydrates, lipids, amino acids, vitamins, trace elements, electrolytes and water. PN should be provided via a central line because of its hypertonicity. However, peripheral PN (with lower nutrient content and larger volume) can be administered via an appropriate non-central line. There are alternatives for the compounding process also, including hospital pharmacy compounded bags and commercial multichamber bags. PN is a costly therapy and has been associated with complications. Metabolic complications related to macro and micronutrient disturbances, such as hyperglycemia, hypertriglyceridemia, and electrolyte imbalance, may occur at any time during PN therapy, as well as infectious complications, mostly related to venous access. Long-term complications, such as hepatobiliary and bone disease are associated with longer PN therapy and home-PN. To prevent and mitigate potential complications, the optimal monitoring and early management of imbalances is required. PN should be prescribed for malnourished patients or high-risk patients with malnutrition where the feasibility of full EN is in question. Several factors should be considered when providing PN, including timing of initiation, clinical status, and risk of complications.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.