Evidence map›Paper›PMID 36364726›Full record

ArticleNutrients2022

Exclusive Enteral Nutrition Exerts Anti-Inflammatory Effects through Modulating Microbiota, Bile Acid Metabolism, and Immune Activities.

Fangfei Xiao, Xuefeng Gao, Hui Hu, Jun Le, Yongheng Chen, Xingsheng Shu, Ziwei Liang, Yang Xu, Yizhong Wang, Ting Zhang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 18 citations in OpenAlex.

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  12. Foods (Basel, Switzerland) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Fangfei XiaoDepartment of Gastroenterology, Hepatology and Nutrition, Shanghai Children's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200062, China.
Xuefeng GaoCentral Laboratory, Shenzhen Key Laboratory of Precision Medicine for Hematological Malignancies, International Cancer Center, Shenzhen University General Hospital, Shenzhen 518000, China.ORCID 0000-0002-1904-392X
Hui HuDepartment of Gastroenterology, Hepatology and Nutrition, Shanghai Children's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200062, China.
Jun LeDepartment of Gastroenterology, Hepatology and Nutrition, Shanghai Children's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200062, China.
Yongheng ChenDepartment of Physiology, School of Basic Medical Sciences, Shenzhen University Health Science Center, Shenzhen 518000, China.
Xingsheng ShuDepartment of Physiology, School of Basic Medical Sciences, Shenzhen University Health Science Center, Shenzhen 518000, China.ORCID 0000-0003-2461-4253
Ziwei LiangSchool of Medicine, Southern University of Science and Technology, Shenzhen 518100, China.
Yang XuSchool of Medicine, Southern University of Science and Technology, Shenzhen 518100, China.
Yizhong WangDepartment of Gastroenterology, Hepatology and Nutrition, Shanghai Children's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200062, China.
Ting ZhangDepartment of Gastroenterology, Hepatology and Nutrition, Shanghai Children's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200062, China.
Shanghai Jiao Tong University · CNShenzhen University Health Science Center · CNSouthern University of Science and Technology · CNShenzhen University · CN

Funding

National Natural Science Foundation of China 81870373National Natural Science Foundation of China 81900474Peacock Talent Programs Research Start-up Grant 802-012677Shanghai Science and Technology Committee 19140904300Shenzhen Key Laboratory Foundation ZDSYS20200811143757022
6 · The paper itself

Abstract

Exclusive enteral nutrition (EEN) can induce remission in patients with pediatric Crohn's disease (CD). This study aims to depict EEN's modification of bile acid (BA) metabolism in pediatric CD and explores the effect of the EEN-enriched BA in inhibiting the inflammatory response. The twelve enrolled pediatric CD patients showed BA dysmetabolism, represented by decreased levels of fecal secondary and unconjugated BAs as determined by UPLC-TQMS, which were accompanied by gut microbiota dysbiosis and reduced BA-metabolizing bacteria including

Indexed as

Enteral NutritionMicrobiotaAnimalsAnti-Inflammatory AgentsBacteriaBile Acids and SaltsCrohn DiseaseLeukocytes, MononuclearMiceRemission InductionAnti-Inflammatory AgentsBile Acids and Saltsbile acidCrohn’s diseaseEENgut microbiotahyocholic acid

Identifiers

PMID36364726
PMCPMC9657881
OpenAlexW4307269955

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.