Evidence map›Paper›PMID 36364650›Full record

ArticleNanomaterials (Basel, Switzerland)2022

New Conjugates Based on AIS/ZnS Quantum Dots and Aluminum Phthalocyanine Photosensitizer: Synthesis, Properties and Some Perspectives.

Dmitry Yakovlev, Ekaterina Kolesova, Svetlana Sizova, Kirill Annas, Marina Tretyak, Victor Loschenov, Anna Orlova, Vladimir Oleinikov

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Dmitry YakovlevShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Science, 117997 Moscow, Russia.
Ekaterina KolesovaFaculty of Photonics, ITMO University, 197101 Saint Petersburg, Russia.ORCID 0000-0002-6730-1858
Svetlana SizovaShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Science, 117997 Moscow, Russia.ORCID 0000-0003-0846-4670
Kirill AnnasFaculty of Photonics, ITMO University, 197101 Saint Petersburg, Russia.
Marina TretyakShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Science, 117997 Moscow, Russia.ORCID 0000-0002-1078-2339
Victor LoschenovProkhorov General Physics Institute, Russian Academy of Science, 119991 Moscow, Russia.ORCID 0000-0002-0507-2367
Anna OrlovaFaculty of Photonics, ITMO University, 197101 Saint Petersburg, Russia.
Vladimir OleinikovShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Science, 117997 Moscow, Russia.
Institute of Bioorganic Chemistry · RUITMO University · RUProkhorov General Physics Institute · RU

Funding

Ministry of Science and Higher Education of the Russian Federation 22-14-00168
6 · The paper itself

Abstract

Today, fluorescent diagnostics and photodynamic therapy are promising methods for diagnosing and treating oncological diseases. The development of new photosensitizers (PS) is one of the most important tasks to improve the efficiency of both laser-induced diagnostics and therapy. In our study, we conjugated PS with AIS/ZnS triple quantum dots (QDs) to obtain non-aggregated complexes. It was shown that the conjugation of PS with QDs does not change the PS fluorescence lifetime, which is a marker of the preservation of PS photophysical properties. In particular, efficient resonant Förster energy transfer (FRET), from QDs to PS molecules in the conjugate, increases the PS luminescence response. The FRET from QD to PS molecules with different ratios of donor and acceptors are shown. It has been demonstrated that the average efficiency of FRET depends on the ratio of PS and QD and reaches a maximum value of 80% at a ratio of 6 PS molecules per 1 QD molecule. Thus, these studies could help to contribute to the development of new complexes based on QD and PS to improve the efficiency of phototheranostics.

Indexed as

aluminum phthalocyanineFRETphotodynamic therapyphotosensitizerquantum dotsreactive oxygen species (ROS)

Identifiers

PMID36364650
PMCPMC9654515
OpenAlexW4308773892

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.