Evidence map›Paper›PMID 36364600›Full record

ArticleNanomaterials (Basel, Switzerland)2022

The Preparation and Biological Testing of Novel Wound Dressings with an Encapsulated Antibacterial and Antioxidant Substance.

Petr Braťka, Taťána Fenclová, Jana Hlinková, Lenka Uherková, Eva Šebová, Veronika Hefka Blahnová, Věra Hedvičáková, Radmila Žižková, Andrej Litvinec, Tomáš Trč and 2 more

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Petr BraťkaFaculty of Biomedical Engineering, Czech Technical University, Náměstí Sítná 3105, 27201 Kladno, Czech Republic.ORCID 0000-0002-9276-7529
Taťána FenclováGrade Medical s.r.o., Náměstí Sítná 3105, 27201 Kladno, Czech Republic.ORCID 0000-0003-3494-9567
Jana HlinkováDepartment of Tissue Engineering, Institute of Experimental Medicine of the Czech Academy of Sciences, Vídeňská 1083, 14220 Prague, Czech Republic.ORCID 0000-0001-7261-1212
Lenka UherkováDepartment of Tissue Engineering, Institute of Experimental Medicine of the Czech Academy of Sciences, Vídeňská 1083, 14220 Prague, Czech Republic.
Eva ŠebováDepartment of Tissue Engineering, Institute of Experimental Medicine of the Czech Academy of Sciences, Vídeňská 1083, 14220 Prague, Czech Republic.ORCID 0000-0002-9592-8279
Veronika Hefka BlahnováDepartment of Tissue Engineering, Institute of Experimental Medicine of the Czech Academy of Sciences, Vídeňská 1083, 14220 Prague, Czech Republic.
Věra HedvičákováDepartment of Tissue Engineering, Institute of Experimental Medicine of the Czech Academy of Sciences, Vídeňská 1083, 14220 Prague, Czech Republic.
Radmila ŽižkováDepartment of Tissue Engineering, Institute of Experimental Medicine of the Czech Academy of Sciences, Vídeňská 1083, 14220 Prague, Czech Republic.ORCID 0000-0002-1679-1877
Andrej LitvinecDepartment of Tissue Engineering, Institute of Experimental Medicine of the Czech Academy of Sciences, Vídeňská 1083, 14220 Prague, Czech Republic.
Tomáš TrčGrade Medical s.r.o., Náměstí Sítná 3105, 27201 Kladno, Czech Republic.
Jozef RosinaFaculty of Biomedical Engineering, Czech Technical University, Náměstí Sítná 3105, 27201 Kladno, Czech Republic.ORCID 0000-0002-5519-3028
Eva FilováDepartment of Tissue Engineering, Institute of Experimental Medicine of the Czech Academy of Sciences, Vídeňská 1083, 14220 Prague, Czech Republic.ORCID 0000-0003-1028-605X
Czech Academy of Sciences · CZGrade Medical (Czechia) · CZCzech Technical University in Prague · CZ

Funding

Czech Academy of Sciences RVO 68378050Ministry of Education, Youth and Sports of the Czech Republic LM2018126 Czech Centre for PhenogenomicsMinistry of Industry and Trade FV30086 and FV40189
6 · The paper itself

Abstract

Chronic wounds represent a significant socio-economic problem, and the improvement of their healing is therefore an essential issue. This paper describes the preparation and biological properties of a novel functionalized nanofiber wound dressing consisting of a polycaprolactone nanofiber carrier modified by a drug delivery system, based on the lipid particles formed by 1-tetradecanol and encapsulated gentamicin and tocopherol acetate. The cytotoxicity of extracts was tested using a metabolic activity assay, and the antibacterial properties of the extracts were tested in vitro on the bacterial strains

Indexed as

antibacterialantioxidantencapsulationin vivonanofiber substratepersonalized carewound dressing

Identifiers

PMID36364600
PMCPMC9656126
OpenAlexW4307945195

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.