Evidence map›Paper›PMID 36364474›Full record

ArticleMolecules (Basel, Switzerland)2022

Synthesis and Cytotoxic Activity of 1,2,4-Triazolo-Linked

Prasanna A Yakkala, Samir R Panda, Syed Shafi, V G M Naidu, M Shahar Yar, Philemon N Ubanako, Samson A Adeyemi, Pradeep Kumar, Yahya E Choonara, Eugene V Radchenko and 2 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Loganic Acid Alleviates the Olfactory-Brain NLRP3 Inflammasome Activation and Rescues Dopaminergic Neurons in Experimental Models of Parkinson's Disease.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2025
    Article
  4. Ambient particulate matter (PMEnvironmental toxicology and pharmacology · 2023
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 3 countries.

Prasanna A YakkalaDepartment of Pharmaceutical Chemistry, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi 110062, India.ORCID 0000-0002-1983-5513
Samir R PandaDepartment of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research (NIPER)-Guwahati, Guwahati 781101, India.ORCID 0000-0001-5327-7917
Syed ShafiDepartment of Chemistry, School of Chemical and Life Sciences, Jamia Hamdard, New Delhi 110062, India.
V G M NaiduDepartment of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research (NIPER)-Guwahati, Guwahati 781101, India.ORCID 0000-0003-1520-2177
M Shahar YarDepartment of Pharmaceutical Chemistry, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi 110062, India.
Philemon N UbanakoWits Advanced Drug Delivery Platform Research Unit, Department of Pharmacy and Pharmacology, School of Therapeutic Sciences, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg 2193, South Africa.
Samson A AdeyemiWits Advanced Drug Delivery Platform Research Unit, Department of Pharmacy and Pharmacology, School of Therapeutic Sciences, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg 2193, South Africa.ORCID 0000-0002-4813-904X
Pradeep KumarWits Advanced Drug Delivery Platform Research Unit, Department of Pharmacy and Pharmacology, School of Therapeutic Sciences, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg 2193, South Africa.ORCID 0000-0002-8640-4350
Yahya E ChoonaraWits Advanced Drug Delivery Platform Research Unit, Department of Pharmacy and Pharmacology, School of Therapeutic Sciences, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg 2193, South Africa.ORCID 0000-0002-3889-1529
Eugene V RadchenkoDepartment of Chemistry, Lomonosov Moscow State University, 119991 Moscow, Russia.ORCID 0000-0002-2091-7022
Vladimir A PalyulinDepartment of Chemistry, Lomonosov Moscow State University, 119991 Moscow, Russia.ORCID 0000-0001-8792-8386
Ahmed KamalDepartment of Pharmaceutical Chemistry, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi 110062, India.
Jamia Hamdard · INUniversity of the Witwatersrand · ZALomonosov Moscow State University · RUNational Institute of Pharmaceutical Education and Research · IN

Funding

Department of Science and Technology DST/IMRCD/BRICS/PilotCall2/CCT/2018
6 · The paper itself

Abstract

A series of new 1,2,4-triazolo-linked

Indexed as

Antineoplastic AgentsTankyrasesApoptosisbeta CateninCell Line, TumorCell ProliferationDrug Screening Assays, AntitumorFluorouracilHumansMolecular StructureOxygen RadioisotopesPhosphatidylinositol 3-KinasesReactive Oxygen SpeciesAntineoplastic Agentsbeta CateninFluorouracilOxygen-15Oxygen RadioisotopesPhosphatidylinositol 3-KinasesReactive Oxygen SpeciesTankyrases1,2,4-triazolo bis-indolyl conjugatescolon cancercytotoxicityPI3K/tankyrase inhibitorsβ-catenin pathway

Identifiers

PMID36364474
PMCPMC9657870
OpenAlexW4308547877

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.