Evidence map›Paper›PMID 36364471›Full record

ArticleMolecules (Basel, Switzerland)2022

Efficient Synthesis of Fluorescent Coumarins and Phosphorous-Containing Coumarin-Type Heterocycles via Palladium Catalyzed Cross-Coupling Reactions.

Rumen Lyapchev, Ana I Koleva, Iskra Z Koleva, Kristian Subev, Ivelina Madzharova, Kristina B Simeonova, Nevena Petkova-Yankova, Bernd Morgenstern, Vesela Lozanova, Petar Y Petrov and 1 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Rumen LyapchevFaculty of Chemistry and Pharmacy, Sofia University "St. Kliment Ohridski", 1164 Sofia, Bulgaria.
Ana I KolevaFaculty of Chemistry and Pharmacy, Sofia University "St. Kliment Ohridski", 1164 Sofia, Bulgaria.ORCID 0000-0001-7702-0315
Iskra Z KolevaFaculty of Chemistry and Pharmacy, Sofia University "St. Kliment Ohridski", 1164 Sofia, Bulgaria.ORCID 0000-0002-4080-9846
Kristian SubevFaculty of Chemistry and Pharmacy, Sofia University "St. Kliment Ohridski", 1164 Sofia, Bulgaria.
Ivelina MadzharovaFaculty of Chemistry and Pharmacy, Sofia University "St. Kliment Ohridski", 1164 Sofia, Bulgaria.
Kristina B SimeonovaFaculty of Chemistry and Pharmacy, Sofia University "St. Kliment Ohridski", 1164 Sofia, Bulgaria.ORCID 0000-0001-9078-1223
Nevena Petkova-YankovaFaculty of Chemistry and Pharmacy, Sofia University "St. Kliment Ohridski", 1164 Sofia, Bulgaria.ORCID 0000-0003-1885-412X
Bernd MorgensternDepartment of Inorganic Solid-State Chemistry, Saarland University, 66123 Saarbrücken, Germany.
Vesela LozanovaDepartment of Medicinal Chemistry and Biochemistry, Medicinal University of Sofia, 1431 Sofia, Bulgaria.ORCID 0000-0002-7748-4133
Petar Y PetrovFaculty of Chemistry and Pharmacy, Sofia University "St. Kliment Ohridski", 1164 Sofia, Bulgaria.
Rositca D NikolovaFaculty of Chemistry and Pharmacy, Sofia University "St. Kliment Ohridski", 1164 Sofia, Bulgaria.ORCID 0000-0003-0671-0532
Sofia University "St. Kliment Ohridski" · BGSaarland University · DE

Funding

National Science Fund KP-06-М-59/6 from 19.11.2021
6 · The paper itself

Abstract

Quantum-chemical calculations on the spectral properties of some aryl substituted 3-phosphonocoumarins were performed, and the effect of the substituents in the aryl moiety was evaluated. The structures possessing promising fluorescent properties were successfully synthesized via Suzuki and Sonogashira cross-coupling. The synthetic protocol was also applied for the phosphorous chemoisomer of 3-phosphonocoumarin, 1,2-benzoxaphosphorin, and their carboxylate analogues. The optical properties of the arylated and alkynylated products were experimentally determined. The obtained quantum-chemical and experimental results give the possibility for a fine tuning of the optical properties of phosphorous-containing coumarin systems by altering the substituent at its C-6 position.

Indexed as

CoumarinsPalladiumCatalysisColoring AgentsMolecular StructureColoring AgentscoumarinCoumarinsPalladium1,2-benzoxaphosphorin3-phosphonocoumarincoumarin-3-carboxylatescross-couplingDFT calculationsfluorescencePd-catalyzed reactionsphotophysical propertiesSonogashira reactionSuzuki reaction

Identifiers

PMID36364471
PMCPMC9654183
OpenAlexW4308531827

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.