Evidence map›Paper›PMID 36364412›Full record

ReviewMolecules (Basel, Switzerland)2022

Bispyrrolidinoindoline Epi(poly)thiodioxopiperazines (BPI-ETPs) and Simplified Mimetics: Structural Characterization, Bioactivities, and Total Synthesis.

Claudio Martínez, Patricia García-Domínguez, Rosana Álvarez, Angel R de Lera

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Claudio MartínezCINBIO, ORCHID Group, Departmento de Química Orgánica, Universidade de Vigo, 36310 Vigo, Spain.
Patricia García-DomínguezCINBIO, ORCHID Group, Departmento de Química Orgánica, Universidade de Vigo, 36310 Vigo, Spain.
Rosana ÁlvarezCINBIO, ORCHID Group, Departmento de Química Orgánica, Universidade de Vigo, 36310 Vigo, Spain.ORCID 0000-0001-5608-7561
Angel R de LeraCINBIO, ORCHID Group, Departmento de Química Orgánica, Universidade de Vigo, 36310 Vigo, Spain.ORCID 0000-0001-6896-9078

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Within the 2,5-dioxopiperazine-containing natural products generated by "head-to-tail" cyclization of peptides, those derived from tryptophan allow further structural diversification due to the rich chemical reactivity of the indole heterocycle, which can generate tetracyclic fragments of hexahydropyrrolo[2,3-

Indexed as

AlkaloidsBiological ProductsCyclizationIndole AlkaloidsIndolesTryptophanAlkaloidsBiological ProductsIndole AlkaloidsIndolesTryptophanbioactivitiesbispyrrolidinoindoline epi(poly)thiodioxopiperazine alkaloidsisolationstructural elucidationsynthetic analogstotal synthesis

Identifiers

PMID36364412
PMCPMC9659040

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.