Evidence map›Paper›PMID 36364300›Full record

ArticleMolecules (Basel, Switzerland)2022

Microwave-Assisted Extraction of Bioactive Compounds from Lentil Wastes: Antioxidant Activity Evaluation and Metabolomic Characterization.

Maria Maddalena Cavalluzzi, Antonella Lamonaca, Natalie Paola Rotondo, Daniela Valeria Miniero, Marilena Muraglia, Paola Gabriele, Filomena Corbo, Annalisa De Palma, Roberta Budriesi, Elisabetta De Angelis and 2 more

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Valorization of Mushroom Residues for Functional Food Packaging.International journal of molecular sciences · 2025
    Review
  3. Microwave-Assisted Extraction ofJournal of fungi (Basel, Switzerland) · 2025
    Article
  4. Exploitation of ApulianMolecules (Basel, Switzerland) · 2025
    Article
  5. From waste to value: Integrating legume byproducts into sustainable industrialization.Comprehensive reviews in food science and food safety · 2025
    Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Hypoglycemic Properties ofJournal of fungi (Basel, Switzerland) · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Biostimulant Formulations andMolecules (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Maria Maddalena CavalluzziDepartment of Pharmacy-Drug Sciences, University Aldo Moro-Bari, Via Orabona 4, 70126 Bari, Italy.ORCID 0000-0002-3402-8170
Antonella LamonacaInstitute of Sciences of Food Production, National Research Council of Italy (CNR-ISPA), Via Amendola 122/O, 70126 Bari, Italy.
Natalie Paola RotondoDepartment of Pharmacy-Drug Sciences, University Aldo Moro-Bari, Via Orabona 4, 70126 Bari, Italy.
Daniela Valeria MinieroDepartment of Biosciences, Biotechnologies and Biopharmaceutics, University Aldo Moro-Bari, Via Orabona 4, 70126 Bari, Italy.ORCID 0000-0002-3324-9692
Marilena MuragliaDepartment of Pharmacy-Drug Sciences, University Aldo Moro-Bari, Via Orabona 4, 70126 Bari, Italy.
Paola GabrieleDepartment of Pharmacy-Drug Sciences, University Aldo Moro-Bari, Via Orabona 4, 70126 Bari, Italy.
Filomena CorboDepartment of Pharmacy-Drug Sciences, University Aldo Moro-Bari, Via Orabona 4, 70126 Bari, Italy.ORCID 0000-0002-6951-1103
Annalisa De PalmaDepartment of Biosciences, Biotechnologies and Biopharmaceutics, University Aldo Moro-Bari, Via Orabona 4, 70126 Bari, Italy.ORCID 0000-0001-6391-529X
Roberta BudriesiDepartment of Pharmacy and Biotechnology, Food Chemistry and Nutraceutical Lab, Alma Mater Studiorum-University of Bologna, 40126 Bologna, Italy.ORCID 0000-0002-8454-9740
Elisabetta De AngelisInstitute of Sciences of Food Production, National Research Council of Italy (CNR-ISPA), Via Amendola 122/O, 70126 Bari, Italy.ORCID 0000-0003-1290-4544
Linda MonaciInstitute of Sciences of Food Production, National Research Council of Italy (CNR-ISPA), Via Amendola 122/O, 70126 Bari, Italy.ORCID 0000-0001-5650-7909
Giovanni LentiniDepartment of Pharmacy-Drug Sciences, University Aldo Moro-Bari, Via Orabona 4, 70126 Bari, Italy.ORCID 0000-0001-7079-5994

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The recovery of industrial by-products is part of the zero-waste circular economy. Lentil seed coats are generally considered to be a waste by-product. However, this low-value by-product is rich in bioactive compounds and may be considered an eco-friendly source of health-promoting phytochemicals. For the first time, a sustainable microwave-assisted extraction technique was applied, and a solvent screening was carried out to enhance the bioactive compound content and the antioxidant activity of green and red lentil hull extracts. With respect to green lentil hull extracts that were obtained with different solvents, the aqueous extract of the red lentil seed coats showed the highest total phenolic and total flavonoid content (TPC = 28.3 ± 0.1 mg GAE/g dry weight, TFC = 1.89 ± 0.01 mg CE/100 mg dry weight, respectively), as well as the highest antioxidant activity, both in terms of the free radical scavenging activity (ABTS, 39.06 ± 0.73 mg TE/g dry weight; DPPH, IC

Indexed as

Lens PlantNeuroblastomaAntioxidantsHumansMicrowavesPlant ExtractsSolventsAntioxidantsPlant ExtractsSolventsantioxidant activitycircular economylentil hullsliquid chromatography-high resolution mass spectrometrymicrowave-assisted extraction

Identifiers

PMID36364300
PMCPMC9655545

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.