Composite Hydrogel Microspheres Encapsulating Hollow Mesoporous Imprinted Nanoparticles for Selective Capture and Separation of 2'-Deoxyadenosine.

Lu Liu, Mengdie Zhou, Jianming Pan

Open access · goldAbstract read

In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

0.6field-weighted citation impact, top 39% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 7 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Lu LiuSchool of Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang 212013, China.ORCID 0000-0002-9727-5750

Mengdie ZhouSchool of Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang 212013, China.

Jianming PanSchool of Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang 212013, China.

Jiangsu University · CN

Funding

Jiangsu Agricultural Independent Innovation Fund Project CX(21)3079Jiangsu Key Research and Development Program BE2022356Key Research and Development Program of Zhenjiang City SH2020014National Natural Science Foundation of China 22078132Open Funding Project of the National Key Laboratory of Biochemical Engineering 2021KF-02

6 · The paper itself

Abstract

Hollow mesoporous silica nanoparticles have been widely applied as a carrier material in the molecular imprinting process because of their excellent properties, with high specific surface area and well-defined active centers. However, these kinds of materials face the inevitable problem that they have low mass transfer efficiency and cannot be conveniently recycled. In order to solve this problem, this work has developed a composite hydrogel microsphere (MMHSG) encapsulated with hollow mesoporous imprinted nanoparticles for the selective extraction of 2'-deoxyadenosine (dA). Subsequently, the hollow mesoporous imprinted polymers using dA as template molecule and synthesized 5-(2-carbomethoxyvinyl)-2'-deoxyuridine (AcrU) as functional monomer were encapsulated in hydrogel. MMHSG displayed good performance in specifically recognizing and quickly separating dA, whereas no imprinting effect was observed among 2'-deoxyguanosine (dG), deoxycytidine (dC), or 5'-monophosphate disodium salt (AMP). Moreover, the adsorption of dA by MMHSG followed chemisorption and could reach adsorption equilibrium within 60 min; the saturation adsorption capacity was 20.22 μmol·g

Indexed as

Molecular ImprintingNanoparticlesAdsorptionDeoxyadenosinesHydrogelsMicrospheresSilicon Dioxide2'-deoxyadenosineDeoxyadenosinesHydrogelsSilicon Dioxide2’-deoxyadenosinehollow mesoporous nanoparticleshydrogel microspheresmolecularly imprinted polymersselective adsorption

Identifiers

PMID36364271

DOI10.3390/molecules27217444

PMCPMC9659214

OpenAlexW4308122145

What OpenQuestion holds

Textmetadata

LicenceCC BY

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.