Evidence map›Paper›PMID 36364243›Full record

ArticleMolecules (Basel, Switzerland)2022

First Evidence of Anti-Steatotic Action of Macrotympanain A1, an Amphibian Skin Peptide from

Ilaria Demori, Zeinab El Rashed, Giulia De Negri Atanasio, Alice Parodi, Enrico Millo, Annalisa Salis, Andrea Costa, Giacomo Rosa, Matteo Zanotti Russo, Sebastiano Salvidio and 2 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Ilaria DemoriDepartment of Earth, Environmental, and Life Sciences (DISTAV), University of Genoa, Corso Europa 26, 16132 Genoa, Italy.
Zeinab El RashedDepartment of Earth, Environmental, and Life Sciences (DISTAV), University of Genoa, Corso Europa 26, 16132 Genoa, Italy.
Giulia De Negri AtanasioDepartment of Earth, Environmental, and Life Sciences (DISTAV), University of Genoa, Corso Europa 26, 16132 Genoa, Italy.
Alice ParodiDepartment of Experimental Medicine (DIMES), Section of Biochemistry, University of Genoa, Viale Benedetto XV 1, 16132 Genoa, Italy.
Enrico MilloDepartment of Experimental Medicine (DIMES), Section of Biochemistry, University of Genoa, Viale Benedetto XV 1, 16132 Genoa, Italy.ORCID 0000-0002-4019-0051
Annalisa SalisDepartment of Experimental Medicine (DIMES), Section of Biochemistry, University of Genoa, Viale Benedetto XV 1, 16132 Genoa, Italy.ORCID 0000-0002-3082-2908
Andrea CostaDepartment of Earth, Environmental, and Life Sciences (DISTAV), University of Genoa, Corso Europa 26, 16132 Genoa, Italy.ORCID 0000-0003-4273-6182
Giacomo RosaDepartment of Earth, Environmental, and Life Sciences (DISTAV), University of Genoa, Corso Europa 26, 16132 Genoa, Italy.
Matteo Zanotti RussoAngel Consulting, Via San Senatore 14, 20122 Milano, Italy.
Sebastiano SalvidioDepartment of Earth, Environmental, and Life Sciences (DISTAV), University of Genoa, Corso Europa 26, 16132 Genoa, Italy.ORCID 0000-0003-2247-8307
Katia CorteseDepartment of Experimental Medicine (DIMES), Cellular Electron Microscopy Laboratory, University of Genoa, Via Antonio de Toni 14, 16132 Genoa, Italy.ORCID 0000-0001-9218-8933
Elena GrasselliDepartment of Earth, Environmental, and Life Sciences (DISTAV), University of Genoa, Corso Europa 26, 16132 Genoa, Italy.ORCID 0000-0003-4439-4059
University of Genoa · ITUniversity of Pisa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many different amphibian skin peptides have been characterized and proven to exert various biological actions, such as wound-healing, immunomodulatory, anti-oxidant, anti-inflammatory and anti-diabetic effects. In this work, the possible anti-steatotic effect of macrotympanain A1 (MA1) (FLPGLECVW), a skin peptide isolated from the Chinese odorous frog

Indexed as

Fatty LiverAnimalsPeptidesPPAR gammaRanidaeRatsSkinPeptidesPPAR gammaamphibian skin peptidesanti-steatoticliverNAFLDperilipins (PLINs)peroxisome proliferator-activated receptors (PPARs)triglycerides

Identifiers

PMID36364243
PMCPMC9656375
OpenAlexW4308119600

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.