Evidence map›Paper›PMID 36364193›Full record

ArticleMolecules (Basel, Switzerland)2022

The Design of Rapid Self-Healing Alginate Hydrogel with Dendritic Crosslinking Network.

Dingxuan Wang, Yuhan Li, Haobo Zhang, Zhaorong Ren, Kefan Fan, Jue Cheng, Junying Zhang, Feng Gao

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 9 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Dingxuan WangSchool of Material Science and Engineering, Beijing University of Chemistry Technology, Beijing 100029, China.
Yuhan LiSchool of Material Science and Engineering, Beijing University of Chemistry Technology, Beijing 100029, China.
Haobo ZhangSchool of Material Science and Engineering, Beijing University of Chemistry Technology, Beijing 100029, China.
Zhaorong RenSchool of Material Science and Engineering, Beijing University of Chemistry Technology, Beijing 100029, China.
Kefan FanSchool of Material Science and Engineering, Beijing University of Chemistry Technology, Beijing 100029, China.
Jue ChengSchool of Material Science and Engineering, Beijing University of Chemistry Technology, Beijing 100029, China.
Junying ZhangSchool of Material Science and Engineering, Beijing University of Chemistry Technology, Beijing 100029, China.
Feng GaoSchool of Material Science and Engineering, Beijing University of Chemistry Technology, Beijing 100029, China.ORCID 0000-0002-3146-4006
Beijing University of Chemical Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Self-healing alginate hydrogels play important roles in the biological field due to their biocompatibility and ability to recover after cracking. One of the primary targets for researchers in this field is to increase the self-healing speed. Sodium alginate was oxidized, generating aldehyde groups on the chains, which were then crosslinked by poly(amino) amine (PAMAM) via Schiff base reaction. The dendritic structure was introduced to the alginate hydrogel in this work, which was supposed to promote intermolecular interactions and accelerate the self-healing process. Results showed that the hydrogel (ADA-PAMAM) formed a gel within 2.5 min with stable rheological properties. Within 25 min, the hydrogel recovered under room temperature. Furthermore, the aldehyde degree of alginate dialdehyde with a different oxidation degree was characterized through gel permeation chromatograph aligned with multi-angle laser light scattering and ultraviolet (UV) absorption. The chemical structure of the hydrogel was characterized through Fourier transform infrared spectroscopy and UV-vis spectra. The SEM and laser scanning confocal microscope (CLSM) presented the antibiotic ability of ADA-PAMAM against both

Indexed as

AlginatesHydrogelsAldehydesBiocompatible MaterialsEscherichia coliStaphylococcus aureusAldehydesAlginatesBiocompatible MaterialsHydrogelsalginate hydrogeldendritic crosslinking networkPAMAMrapid self-healing

Identifiers

PMID36364193
PMCPMC9655740
OpenAlexW4307944280

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.