Evidence map›Paper›PMID 36364071›Full record

ArticleMolecules (Basel, Switzerland)2022

Multitargeted Molecular Docking and Dynamic Simulation Studies of Bioactive Compounds from

Fatima Javed Mirza, Saadia Zahid, Sanila Amber, Sumera, Hira Jabeen, Noreen Asim, Syed Adnan Ali Shah

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 28 citations in OpenAlex.

  1. Exploring the Neuroprotective Effects of Walnut (International journal of molecular sciences · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Role of Saponins fromMolecules (Basel, Switzerland) · 2025
    Article
  7. Review
  8. Determination of Potential Lead Compound fromInternational journal of molecular sciences · 2024
    Article
  9. Article
  10. Article
  11. Deciphering Neuroprotective Effect ofCurrent drug targets · 2024
    Review
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Fatima Javed MirzaNeurobiology Laboratory, Atta ur Rahman School of Applied Biosciences, National University of Sciences and Technology, Islamabad 44000, Pakistan.
Saadia ZahidNeurobiology Laboratory, Atta ur Rahman School of Applied Biosciences, National University of Sciences and Technology, Islamabad 44000, Pakistan.ORCID 0000-0003-1667-554X
Sanila AmberNeurobiology Laboratory, Atta ur Rahman School of Applied Biosciences, National University of Sciences and Technology, Islamabad 44000, Pakistan.
SumeraNeurobiology Laboratory, Atta ur Rahman School of Applied Biosciences, National University of Sciences and Technology, Islamabad 44000, Pakistan.
Hira JabeenCenter for Computational Chemistry, School of Chemistry, University of Bristol, Bristol BS8 1TH, UK.
Noreen AsimInstitute of Biotechnology and Genetic Engineering, The University of Agriculture, Peshawar 25130, Pakistan.
Syed Adnan Ali ShahFaculty of Pharmacy, Universiti Teknologi MARA Cawangan Selangor Kampus Puncak Alam, Bandar Puncak Alam 42300, Malaysia.ORCID 0000-0002-8142-5013
National University of Sciences and Technology · PKThe University of Agriculture, Peshawar · PKUniversiti Teknologi MARA · MYUniversity of Bristol · GB

Funding

Higher Education Commission 5019
6 · The paper itself

Abstract

Alzheimer's disease (AD) has been associated with the hallmark features of cholinergic dysfunction, amyloid beta (Aβ) aggregation and impaired synaptic transmission, which makes the associated proteins, such as β-site amyloid precursor protein cleaving enzyme 1 (BACE I), acetylcholine esterase (AChE) and synapsin I, II and III, major targets for therapeutic intervention. The present study investigated the therapeutic potential of three major phytochemicals of

Indexed as

Alzheimer DiseaseRosmarinusAcetylcholinesteraseAmyloid beta-PeptidesAmyloid Precursor Protein SecretasesAspartic Acid EndopeptidasesCholinesterase InhibitorsMolecular Docking SimulationMolecular Dynamics SimulationSynapsinsAcetylcholinesteraseAmyloid beta-PeptidesAmyloid Precursor Protein SecretasesAspartic Acid EndopeptidasesCholinesterase InhibitorsSynapsinsAChEAlzheimer’s diseaseBACE IdockingRosmarinus officinalisSynapsin I, II, III

Identifiers

PMID36364071
PMCPMC9653785
OpenAlexW4307548600

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.