Evidence map›Paper›PMID 36364018›Full record

ArticleMolecules (Basel, Switzerland)2022

Valorization of Phenolic and Carotenoid Compounds of

Elsa F Vieira, Suene Souza, Manuela M Moreira, Rebeca Cruz, Aline Boatto da Silva, Susana Casal, Cristina Delerue-Matos

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Foods (Basel, Switzerland) · 2026
    Review
  2. Article
  3. Molecules (Basel, Switzerland) · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Modeling and Optimization of Phenolic Compounds from Sage (Antioxidants (Basel, Switzerland) · 2023
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Elsa F VieiraREQUIMTE/LAQV, Polytechnic of Porto-School of Engineering (ISEP/IPP), Rua Doctor António Bernardino de Almeida, 4249-015 Porto, Portugal.ORCID 0000-0003-0301-6182
Suene SouzaFaculty of Nutrition and Food Sciences, Rua do Campo Alegre, 4150-180 Porto, Portugal.ORCID 0000-0002-8331-9177
Manuela M MoreiraREQUIMTE/LAQV, Polytechnic of Porto-School of Engineering (ISEP/IPP), Rua Doctor António Bernardino de Almeida, 4249-015 Porto, Portugal.ORCID 0000-0003-1500-9211
Rebeca CruzREQUIMTE/LAQV, Laboratório de Bromatologia e Hidrologia, Faculdade de Farmácia da Universidade do Porto, Rua de Jorge Viterbo Ferreira 228, 4050-313 Porto, Portugal.ORCID 0000-0001-9685-231X
Aline Boatto da SilvaREQUIMTE/LAQV, Laboratório de Bromatologia e Hidrologia, Faculdade de Farmácia da Universidade do Porto, Rua de Jorge Viterbo Ferreira 228, 4050-313 Porto, Portugal.
Susana CasalREQUIMTE/LAQV, Laboratório de Bromatologia e Hidrologia, Faculdade de Farmácia da Universidade do Porto, Rua de Jorge Viterbo Ferreira 228, 4050-313 Porto, Portugal.ORCID 0000-0002-1686-3850
Cristina Delerue-MatosREQUIMTE/LAQV, Polytechnic of Porto-School of Engineering (ISEP/IPP), Rua Doctor António Bernardino de Almeida, 4249-015 Porto, Portugal.ORCID 0000-0002-3924-776X
Rede de Química e Tecnologia · PTUniversidade do Porto · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chayote leaves are known for culinary and traditional medicine applications. This work intended to recover carotenoids and phenolic compounds from chayote leaves using the ultrasound-assisted extraction (UAE). A Box-Behnken design was employed to investigate the impact of extraction time, temperature, and ultrasonic power on the recovery of total carotenoids, total phenolic compounds, and antioxidant activities. For comparative purposes, chayote leaf extracts were prepared by maceration (ME) and microwave-assisted extraction (MAE), using the same time and temperature conditions optimized by UAE. Extraction at 50 °C and 170 Watts for 30 min provided the optimal UAE conditions. UAE showed better extraction efficacy than ME and MAE. The HPLC analysis of the extracts showed that the xanthophyll class was the main class of carotenoids, which constituted 42-85% of the total carotenoid content, followed by β-carotene and tocopherol. Moreover, 26 compounds, classified as phenolic acids, flavonols, flavonoids and other polar compounds, were identified in the chayote leaf extracts. Flavonols accounted for 55% of the total compounds quantified (the major compound was myricetin) and phenolic acids represented around 35%, mostly represented by ferulic acid, chlorogenic acid and (+)-catechin. This study revealed the potential of UAE as an effective green extraction technique to recover bioactive compounds from chayote leaves, for food, and for pharmaceutical and cosmetic applications.

Indexed as

CucurbitaceaeMicrowavesCarotenoidsFlavonolsHydroxybenzoatesPhenolsPlant ExtractsCarotenoidsFlavonolsHydroxybenzoatesphenolic acidPhenolsPlant Extractscarotenoidschayote leavesoptimizationphenolic compoundsultrasound-assisted extraction

Identifiers

PMID36364018
PMCPMC9657614
OpenAlexW4307262105

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.