Evidence map›Paper›PMID 36363975›Full record

ReviewMolecules (Basel, Switzerland)2022

Recent Advances in Exosomal miRNA Biosensing for Liquid Biopsy.

Bingqian Lin, Jinting Jiang, Jingxuan Jia, Xiang Zhou

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Review
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  7. Cancer-associated fibroblasts as a potential therapeutic target for thyroid cancers.International journal of surgery (London, England) · 2026
    Review
  8. Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. Liquid Biopsy in the Clinical Management of Cancers.International journal of molecular sciences · 2024
    Review
  14. Review
  15. Article
  16. Review
  17. Review
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  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Bingqian LinCollege of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, China.
Jinting JiangCollege of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, China.
Jingxuan JiaCollege of Life Sciences, Wuhan University, Wuhan 430072, China.
Xiang ZhouCollege of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, China.

Funding

China Postdoctoral Science Foundation 211000159 to B. L.National Natural Science Foundation of China 91753201, 21721005, and 22037004 to X. Z.
6 · The paper itself

Abstract

As a noninvasive detection technique, liquid biopsy plays a valuable role in cancer diagnosis, disease monitoring, and prognostic assessment. In liquid biopsies, exosomes are considered among the potential biomarkers because they are important bioinformation carriers for intercellular communication. Exosomes transport miRNAs and, thus, play an important role in the regulation of cell growth and function; therefore, detection of cancer cell-derived exosomal miRNAs (exo-miRNAs) gives effective information in liquid biopsy. The development of sensitive, convenient, and reliable exo-miRNA assays will provide new perspectives for medical diagnosis. This review presents different designs and detection strategies of recent exo-miRNA assays in terms of signal transduction and amplification, as well as signal detection. In addition, this review outlines the current attempts at bioassay methods in liquid biopsies. Lastly, the challenges and prospects of exosome bioassays are also considered.

Indexed as

ExosomesMicroRNAsCell ProliferationLiquid BiopsySignal TransductionMicroRNAsbiosensingexosomal miRNAliquid biopsy

Identifiers

PMID36363975
PMCPMC9655350

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.