Evidence map›Paper›PMID 36363935›Full record

ArticleMicromachines2022

Twisted Fiber Optic SPR Sensor for GDF11 Concentration Detection.

Yong Wei, Ze Ran, Rui Wang, Zhuo Ren, Chun-Lan Liu, Chun-Biao Liu, Chen Shi, Chen Wang, Yong-Hui Zhang

Abstract read
In one paragraph

Article in Micromachines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yong WeiCollege of Electronic & Information Engineering, Chongqing Three Gorges University, Chongqing 404100, China.
Ze RanCollege of Electronic & Information Engineering, Chongqing Three Gorges University, Chongqing 404100, China.
Rui WangCollege of Electronic & Information Engineering, Chongqing Three Gorges University, Chongqing 404100, China.
Zhuo RenCollege of Electronic & Information Engineering, Chongqing Three Gorges University, Chongqing 404100, China.
Chun-Lan LiuCollege of Electronic & Information Engineering, Chongqing Three Gorges University, Chongqing 404100, China.
Chun-Biao LiuCollege of Electronic & Information Engineering, Chongqing Three Gorges University, Chongqing 404100, China.
Chen ShiCollege of Electronic & Information Engineering, Chongqing Three Gorges University, Chongqing 404100, China.
Chen WangChongqing Key Laboratory of Development and Utilization of Genuine Medicinal Materials in Three Gorges Reservoir Area, Chongqing Three Gorges Medical College, Chongqing 404120, China.
Yong-Hui ZhangChongqing Key Laboratory of Development and Utilization of Genuine Medicinal Materials in Three Gorges Reservoir Area, Chongqing Three Gorges Medical College, Chongqing 404120, China.

Funding

Chongqing Key Laboratory of Geological Environment Monitoring and Disaster Early-Warning in Three Gorges Reservoir Area ZD2020A0103, ZD2020A0102Chongqing Natural Science Foundation cstc2019jcyj-msxmX0607,cstc2019jcyj-msxmX0431Chongqing Postgraduate Research and Innovation Project NoneFundamental Research Funds for Chongqing Three Gorges University of China No. 19ZDPY08National Natural Science Foundation of China No. 61705025Open Project Program of Chongqing Key Laboratory of Development and Utilization of Genuine Medicinal Materials in Three Gorges Reservoir Area No.KFKT2022005the Science and Technology Project Affiliated to the Education Department of Chongqing Municipality No. KJZD-M202201201
6 · The paper itself

Abstract

There are few methods and insufficient accuracy for growth differentiation factor 11 (GDF11) concentration detection. In this paper, we designed a twisted fiber cladding surface plasmon resonance (SPR) sensor, which can achieve a high precision detection of GDF11 concentration. The new structure of the fiber cladding SPR sensor was realized by coupling the light in the fiber core to the cladding through fiber thermal fusion twisting micromachining technology; a series of functionalized modifications were made to the sensor surface to obtain a fiber sensor capable of GDF11 specific recognition. The experimental results showed when GDF11 antigen concentration was 1 pg/mL-10 ng/mL, the sensor had a detection sensitivity of 2.518 nm/lgC, a detection limit of 0.34 pg/mL, and a good log-linear relationship. The sensor is expected to play a role in the rapid and accurate concentration detection of pathological study for growth differentiation factors.

Indexed as

GDF11 concentration detectiongrowth differentiation factor specific detectionSPR biosensortwisted fiber optic SPR sensor

Identifiers

PMID36363935
PMCPMC9697599

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.