Evidence map›Paper›PMID 36363854›Full record

ArticleMicromachines2022

HT-29 Colon Cancer Cell Electromanipulation and Assessment Based on Their Electrical Properties.

Marius Andrei Olariu, Catalin Tucureanu, Tudor Alexandru Filip, Iuliana Caras, Aurora Salageanu, Valentin Vasile, Marioara Avram, Bianca Tincu, Ina Turcan

Abstract read
In one paragraph

Article in Micromachines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Marius Andrei OlariuDepartment of Electrical Measurements and Materials, Faculty of Electrical Engineering and Information Technology, Gheorghe Asachi Technical University of Iasi, 700050 Iasi, Romania.ORCID 0000-0003-2825-6270
Catalin TucureanuCantacuzino, National Medical-Military Institute for Research and Development, 050096 Bucharest, Romania.
Tudor Alexandru FilipDepartment of Electrical Measurements and Materials, Faculty of Electrical Engineering and Information Technology, Gheorghe Asachi Technical University of Iasi, 700050 Iasi, Romania.ORCID 0000-0002-1647-7124
Iuliana CarasCantacuzino, National Medical-Military Institute for Research and Development, 050096 Bucharest, Romania.
Aurora SalageanuCantacuzino, National Medical-Military Institute for Research and Development, 050096 Bucharest, Romania.ORCID 0000-0003-1567-8650
Valentin VasileCantacuzino, National Medical-Military Institute for Research and Development, 050096 Bucharest, Romania.
Marioara AvramNational Institute for Research and Development in Microtechnologies-IMT Bucharest, 077190 Bucharest, Romania.ORCID 0000-0002-4126-7401
Bianca TincuNational Institute for Research and Development in Microtechnologies-IMT Bucharest, 077190 Bucharest, Romania.ORCID 0000-0003-3784-0807
Ina TurcanDepartment of Electrical Measurements and Materials, Faculty of Electrical Engineering and Information Technology, Gheorghe Asachi Technical University of Iasi, 700050 Iasi, Romania.

Funding

Technical University of Iasi (TUIASI), Romania FCSU-2022
6 · The paper itself

Abstract

This study proposes a feasible approach for the rapid, sensitive, and label-free identification of cancerous cells based on dielectrophoretic (DEP) manipulation and electrical characterization. In this method, the concentration of target cells at the level of customized microelectrodes via DEP is first determined, followed by an electrical impedance evaluation. The study demonstrates the capacity of the methodology to electrically differentiate HT-29 cancer cells from healthy blood cells based on their impedance spectra. Within a higher frequency domain, the electrical impedance of trapped cancer cells was significantly lower compared with the normal ones. In order to evaluate the functionality and reproducibility of the proposed method, the influence of the DEP and EIS (electrical impedance spectroscopy) operating voltages on the electrical characterization of trapped HT-29 cells was analyzed.

Indexed as

cancer cellsdielectrophoresiselectrical impedance spectroscopy

Identifiers

PMID36363854
PMCPMC9698395

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.