Evidence map›Paper›PMID 36363692›Full record

ReviewMicroorganisms2022

Super Shedding in Enteric Pathogens: A Review.

Florent Kempf, Roberto La Ragione, Barbara Chirullo, Catherine Schouler, Philippe Velge

Abstract readReview
In one paragraph

Review in Microorganisms, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Florent KempfINRAE, Université de Tours, ISP, F-37380 Nouzilly, France.ORCID 0000-0002-8801-3601
Roberto La RagioneSchool of Veterinary Medicine, Faculty of Health and Medical Sciences, University of Surrey, Guildford GU2 7XH, UK.
Barbara ChirulloDepartment of Food Safety, Nutrition and Veterinary Public Health, Istituto Superiore di Sanità, Viale Regina Elena 299, 000161 Rome, Italy.ORCID 0000-0002-8403-1829
Catherine SchoulerINRAE, Université de Tours, ISP, F-37380 Nouzilly, France.ORCID 0000-0002-3480-6278
Philippe VelgeINRAE, Université de Tours, ISP, F-37380 Nouzilly, France.ORCID 0000-0002-8201-0194

Funding

Agence Nationale de la Recherche ANR-21-CE20-015-01European Union Horizon 2020 Research and Innovation programme under grant agreement No 773830
6 · The paper itself

Abstract

Super shedding occurs when a small number of individuals from a given host population shed high levels of a pathogen. Beyond this general definition, various interpretations of the shedding patterns have been proposed to identify super shedders, leading to the description of the super shedding phenomenon in a wide range of pathogens, in particular enteric pathogens, which are of considerable interest. Several underlying mechanisms may explain this observation, including factors related to the environment, the gut microbiota, the pathogen itself (i.e., genetic polymorphism), and the host (including immune factors). Moreover, data suggest that the interplay of these parameters, in particular at the host-pathogen-gut microbiota interface, is of crucial importance for the determination of the super shedding phenotype in enteric pathogens. As a phenomenon playing an important role in the epidemics of enteric diseases, the evidence of super shedding has highlighted the need to develop various control strategies.

Indexed as

bacterial polymorphismcontrol strategiesenteric pathogensgut microbiotahost responsesuper shedding

Identifiers

PMID36363692
PMCPMC9692634

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.