Evidence map›Paper›PMID 36363661›Full record

ArticleMembranes2022

Effect of Cobalt Ferrite Nanoparticles in a Hydrophilic Shell on the Conductance of Bilayer Lipid Membrane.

Andrey Anosov, Oksana Koplak, Elena Smirnova, Elizaveta Borisova, Eugenia Korepanova, Alice Derunets

Abstract read
In one paragraph

Article in Membranes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Andrey AnosovThe Department of Medical and Biological Physics, Sechenov First Moscow State Medical University (Sechenov University), 119435 Moscow, Russia.
Oksana KoplakThe Department of Medical and Biological Physics, Sechenov First Moscow State Medical University (Sechenov University), 119435 Moscow, Russia.
Elena SmirnovaThe Department of Medical and Biological Physics, Sechenov First Moscow State Medical University (Sechenov University), 119435 Moscow, Russia.
Elizaveta BorisovaThe Department of Medical and Biological Physics, Sechenov First Moscow State Medical University (Sechenov University), 119435 Moscow, Russia.
Eugenia KorepanovaThe Department of General and Medical Biophysics, Pirogov Russian National Research Medical University, 117997 Moscow, Russia.
Alice DerunetsNational Research Center Kurchatov Institute, Kurchatov Genomic Center, Academician Kurchatov Square 1, 123098 Moscow, Russia.ORCID 0000-0003-1508-1707

Funding

The state task of the Kotelnikov Institute of Radio Engineering and Electronics RAS АААА-А19-119041590070-01
6 · The paper itself

Abstract

We measured the conductance of bilayer lipid membranes of diphytanoylphosphatidylcholine induced by interaction with cubic magnetic nanoparticles (MNPs) of cobalt ferrite 12 and 27 nm in size and coated with a hydrophilic shell. The MNP coating is human serum albumin (HSA) or polyethylene glycol (PEG). The interaction of nanoparticles added to the bulk solution with the lipid bilayer causes the formation of metastable conductive pores, which, in turn, increases the integral conductance of the membranes. The increase in conductance with increasing MNP concentration was practically independent of the particle size. The dependence of the bilayer conductance on the concentration of PEG-coated MNPs was much weaker than that on the concentration with a shell of HSA. Analyzing the current traces, we believe that the conductive pores formed as a result of the interaction of nanoparticles with the membrane can change their size, remaining metastable. The form of multilevel current traces allows us to assume that there are several metastable pore states close in energy. The average radius of the putative cylindrical pores is in the range of 0.4-1.3 nm.

Indexed as

bilayer lipid membraneselectrical conductancelipid poresmagnetic nanoparticles

Identifiers

PMID36363661
PMCPMC9692745

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.