Evidence map›Paper›PMID 36363509›Full record

ReviewMedicina (Kaunas, Lithuania)2022

Particularities of Neurological Manifestations in Adult T-Cell Leukemia/Lymphoma: Need for a Multidisciplinary Approach-A Narrative Review.

Iuliana Iordan, Minodora Onisâi, Ana-Maria Vlădăreanu, Cristina Mambet, Elena Cristina Marinescu, Raluca Nistor, Horia Bumbea

Abstract readReview
In one paragraph

Review in Medicina (Kaunas, Lithuania), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Iuliana IordanDepartment of Hematology, "Carol Davila" University of Medicine and Pharmacy, Emergency University Hospital of Bucharest, 050098 Bucharest, Romania.
Minodora OnisâiDepartment of Hematology, "Carol Davila" University of Medicine and Pharmacy, Emergency University Hospital of Bucharest, 050098 Bucharest, Romania.ORCID 0000-0002-7272-4513
Ana-Maria VlădăreanuDepartment of Hematology, "Carol Davila" University of Medicine and Pharmacy, Emergency University Hospital of Bucharest, 050098 Bucharest, Romania.
Cristina MambetDepartment of Hematology, "Carol Davila" University of Medicine and Pharmacy, Emergency University Hospital of Bucharest, 050098 Bucharest, Romania.
Elena Cristina MarinescuDepartment of Hematology, "Carol Davila" University of Medicine and Pharmacy, Emergency University Hospital of Bucharest, 050098 Bucharest, Romania.
Raluca NistorDepartment of Neurology, "Carol Davila" University of Medicine and Pharmacy, Emergency University Hospital of Bucharest, 050098 Bucharest, Romania.
Horia BumbeaDepartment of Hematology, "Carol Davila" University of Medicine and Pharmacy, Emergency University Hospital of Bucharest, 050098 Bucharest, Romania.ORCID 0000-0002-3706-3166

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ATL is a rare but a highly aggressive T-cell neoplasm associated with human T-cell leukemia virus-1 (HTLV-1) infection. Human T-cell lymphotropic virus type-1 (HTLV-1) is a oncogenic retrovirus responsible for the development of adult T-cell leukemia (ATL), but also for other non-malignant diseases, such as HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). HTLV-1 has a higher prevalence in Japan, the Caribbean, South America, intertropical Africa, Romania, and northern Iran. ATL patients can have an extensive spectrum of neurological manifestations. Numerous factors can be implicated, such as central nervous system infiltrates, neurolymphomatosis, complications to medication or allogeneic stem cell transplantation, HAM/TSP, infections, metabolic disturbances. The neurological complications are not always easy to recognize and treat. Thus, this review underlines the necessity of a multidisciplinary approach in ATL patients with neurological symptomatology.

Indexed as

Human T-lymphotropic virus 1Leukemia-Lymphoma, Adult T-CellParaparesis, Tropical SpasticAdultAfricaCentral Nervous SystemHumansATLCNS involvementHAM/TSPinfectionneurological manifestationsneurolymphomatosis

Identifiers

PMID36363509
PMCPMC9693620

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.