Evidence map›Paper›PMID 36363477›Full record

ArticleMedicina (Kaunas, Lithuania)2022

Perioperative Red Cell Line Trend following Robot-Assisted Radical Prostatectomy for Prostate Cancer.

Francesco Di Bello, Ernesto Di Mauro, Claudia Collà Ruvolo, Massimiliano Creta, Roberto La Rocca, Giuseppe Celentano, Marco Capece, Luigi Napolitano, Simone Morra, Gabriele Pezone and 10 more

Abstract read
In one paragraph

Article in Medicina (Kaunas, Lithuania), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Francesco Di BelloDepartment of Neuroscience, Reproductive and Odontostomatological Sciences, University of Naples "Federico II", Via Pansini, 80138 Naples, Italy.
Ernesto Di MauroDepartment of Neuroscience, Reproductive and Odontostomatological Sciences, University of Naples "Federico II", Via Pansini, 80138 Naples, Italy.
Claudia Collà RuvoloDepartment of Neuroscience, Reproductive and Odontostomatological Sciences, University of Naples "Federico II", Via Pansini, 80138 Naples, Italy.ORCID 0000-0001-8110-7341
Massimiliano CretaDepartment of Neuroscience, Reproductive and Odontostomatological Sciences, University of Naples "Federico II", Via Pansini, 80138 Naples, Italy.ORCID 0000-0003-2082-3330
Roberto La RoccaDepartment of Neuroscience, Reproductive and Odontostomatological Sciences, University of Naples "Federico II", Via Pansini, 80138 Naples, Italy.
Giuseppe CelentanoDepartment of Neuroscience, Reproductive and Odontostomatological Sciences, University of Naples "Federico II", Via Pansini, 80138 Naples, Italy.ORCID 0000-0002-3346-8385
Marco CapeceDepartment of Neuroscience, Reproductive and Odontostomatological Sciences, University of Naples "Federico II", Via Pansini, 80138 Naples, Italy.ORCID 0000-0002-1951-404X
Luigi NapolitanoDepartment of Neuroscience, Reproductive and Odontostomatological Sciences, University of Naples "Federico II", Via Pansini, 80138 Naples, Italy.ORCID 0000-0003-2036-0356
Simone MorraDepartment of Neuroscience, Reproductive and Odontostomatological Sciences, University of Naples "Federico II", Via Pansini, 80138 Naples, Italy.
Gabriele PezoneDepartment of Neuroscience, Reproductive and Odontostomatological Sciences, University of Naples "Federico II", Via Pansini, 80138 Naples, Italy.
Francesco PassaroDepartment of Neuroscience, Reproductive and Odontostomatological Sciences, University of Naples "Federico II", Via Pansini, 80138 Naples, Italy.
Ciro De LucaDepartment of Neuroscience, Reproductive and Odontostomatological Sciences, University of Naples "Federico II", Via Pansini, 80138 Naples, Italy.
Francesco MangiapiaDepartment of Neuroscience, Reproductive and Odontostomatological Sciences, University of Naples "Federico II", Via Pansini, 80138 Naples, Italy.
Nicola LogriecoDepartment of Neuroscience, Reproductive and Odontostomatological Sciences, University of Naples "Federico II", Via Pansini, 80138 Naples, Italy.
Pasquale BuonannoDepartment of Neuroscience, Reproductive and Odontostomatological Sciences, University of Naples "Federico II", Via Pansini, 80138 Naples, Italy.
Giuseppe ServilloDepartment of Neuroscience, Reproductive and Odontostomatological Sciences, University of Naples "Federico II", Via Pansini, 80138 Naples, Italy.
Ciro ImbimboDepartment of Neuroscience, Reproductive and Odontostomatological Sciences, University of Naples "Federico II", Via Pansini, 80138 Naples, Italy.
Vincenzo MironeDepartment of Neuroscience, Reproductive and Odontostomatological Sciences, University of Naples "Federico II", Via Pansini, 80138 Naples, Italy.
Nicola LongoDepartment of Neuroscience, Reproductive and Odontostomatological Sciences, University of Naples "Federico II", Via Pansini, 80138 Naples, Italy.
Gianluigi CalifanoDepartment of Neuroscience, Reproductive and Odontostomatological Sciences, University of Naples "Federico II", Via Pansini, 80138 Naples, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Objective: Blood loss represents a long-standing concern of radical prostatectomy (RP). This study aimed to assess how red line cell values changed following robot-assisted radical prostatectomy (RARP) for prostate cancer (PCa). Materials and Methods: The blood panels of 453 consecutive PCa patients undergoing RARP at a single tertiary academic referral center, from September 2020 to April 2022, were reviewed. Data from 363 patients with the blood panel available for the following timeframe: within seven days before surgery, six hours after surgery, and the first three postoperative days, were analyzed. Specifically, hemoglobin (Hb, g/dL), red blood cells (RBCs, ×106/μL), and hematocrit (HCT, %) trends were collected. Results: Considering the Hb trend, the median values in the preoperative day, postoperative day (POD) 2, and POD 3 are 14.7 (interquartile range (IQR) = 13.9−15.4), 12.1 (IQR = 11.2−12.9), and 12.2 (IQR = 11.2−13.1), respectively. The ∆ between preoperative day and POD 2 is 2.5 (IQR = 1.8−3.2) (p < 0.001). Considering the RBCs trend, the median values in the preoperative day, POD 2, and POD 3 are 4.9 (IQR = 4.7−5.3), 4.1 (IQR = 3.8−4.4), and 4.1 (IQR = 3.8−4.5), respectively. The ∆ between preoperative day and POD 2 is 0.9 (IQR = 0.6−1.1) (p < 0.001). Considering the HCT trend, the median values in the preoperative day, POD 2, and POD 3 are 44.4 (IQR = 41.7−46.6), 36.4 (IQR = 33.8−38.9), and 36.1 (IQR = 33.5−38.7), respectively. The ∆ between preoperative day and POD 2 is 7.8 (IQR = 5.2−10.5) (p < 0.001). Conclusions: Overall, patients undergoing RARP experience a significant, but clinically limited, decline in red line cell values between the preoperative time and the second day post-surgery. These observations are important to provide physicians with knowledge of the expected postoperative course and, thus, to improve the quality of patient care.

Indexed as

Prostatic NeoplasmsRoboticsRobotic Surgical ProceduresCell LineErythrocytesHumansMaleProstatectomyTreatment Outcomeblood losshematocrithemoglobinPCaRARPred blood cellsurgerysurgical oncology

Identifiers

PMID36363477
PMCPMC9695953

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.