Evidence map›Paper›PMID 36363255›Full record

ArticleMaterials (Basel, Switzerland)2022

Correlations on the Structure and Properties of Collagen Hydrogels Produced by E-Beam Crosslinking.

Maria Demeter, Ion Călina, Anca Scărișoreanu, Marin Micutz, Mădălina Albu Kaya

Open access · goldAbstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 36 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Maria DemeterNational Institute for Lasers, Plasma and Radiation Physics (INFLPR), Atomiştilor 409, 077125 Măgurele, Romania.ORCID 0000-0003-0758-1445
Ion CălinaNational Institute for Lasers, Plasma and Radiation Physics (INFLPR), Atomiştilor 409, 077125 Măgurele, Romania.ORCID 0000-0003-2828-3471
Anca ScărișoreanuNational Institute for Lasers, Plasma and Radiation Physics (INFLPR), Atomiştilor 409, 077125 Măgurele, Romania.
Marin MicutzDepartment of Physical Chemistry, University of Bucharest, 4-12 Regina Elisabeta Blvd., 030018 Bucharest, Romania.ORCID 0000-0001-6149-0371
Mădălina Albu KayaDepartment of Collagen, Division Leather and Footwear Research Institute, National Research and Development Institute for Textiles and Leather (INCDTP), 93 Ion Minulescu Str., 031215 Bucharest, Romania.ORCID 0000-0001-9960-2244
National Institute for Laser Plasma and Radiation Physics · RONational Research & Development Institute for Textiles and Leather · ROUniversity of Bucharest · RO

Funding

Ministerul Cercetării și Inovării CNCS-UEFISCDI, project number PN-III-P1-1.1-PD-2021-0552, within PNCDI IIIMinisterul Cercetării și Inovării Romanian National Nucleu Program LAPLAS VI-contract no. 16N/2019National Interest Facilities National Institute for Lasers, Plasma and Radiation Physics Electron Accelerators Laboratory
6 · The paper itself

Abstract

In this study, a collagen hydrogel using collagen exclusively produced in Romania, was obtained by electron beam (e-beam) crosslinking. The purpose of our study is to obtain new experimental data on the crosslinking of collagen and to predict as faithfully as possible, its behavior at high irradiation doses and energies. To pursue this, the correlations between macromolecular structure and properties of collagen hydrogels were determined by rheological analysis, Fourier Transform Infrared Spectroscopy (FTIR), Scanning Electron Microscopy (SEM), and Differential Scanning Calorimetry (DSC), respectively. The gel fraction, swelling degree, and network parameters of the collagen hydrogels were also investigated at different irradiation doses. Through experimental exploration, we concluded that irradiation with e-beam up to 25 kGy induces crosslinking processes in collagen structure without producing advanced degradation processes. E-beam technology is a great method to develop new materials for medical applications without adding other chemical reagents harmful to human health. The future aim is to develop new wound dressings for rapid healing based on collagen, through irradiation technologies.

Indexed as

biomaterialscollagenelectron beam crosslinkinghydrogel

Identifiers

PMID36363255
PMCPMC9658620
OpenAlexW4308128105

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.