Evidence map›Paper›PMID 36362889›Full record

ArticleLife (Basel, Switzerland)2022

Associations between Deformation of the Thoracolumbar Fascia and Activation of the Erector Spinae and Multifidus Muscle in Patients with Acute Low Back Pain and Healthy Controls: A Matched Pair Case-Control Study.

Andreas Brandl, Christoph Egner, Rüdiger Reer, Tobias Schmidt, Robert Schleip

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Life (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07244913 (Therapeutic Effects of Instrument-assisted Versus Sound-assisted Soft Tissue Mobilization Among Patients With Chronic Non-specific Low Back Pain), which is not on this map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07244913 narecruitingnot on this mapstarted 2025, after this paper: background citation

Therapeutic Effects of Instrument-assisted Versus Sound-assisted Soft Tissue Mobilization Among Patients With Chronic Non-specific Low Back Pain

TypeinterventionalSponsorUniversity of LahoreRan2025 to 2026Enrolled60ConditionsChronic Non-Specific Low Back Pain, Pelvic Obliquity, Hamstring Flexibility, Physical FunctionArmsSASTM, IASTM, Exercise
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

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  15. Quantity and Distribution of Muscle Spindles in Animal and Human Muscles.International journal of molecular sciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Andreas BrandlDepartment of Sports Medicine, Institute for Human Movement Science, Faculty for Psychology and Human Movement Science, University of Hamburg, 20148 Hamburg, Germany.
Christoph EgnerDepartment for Medical Professions, Diploma Hochschule, 37242 Bad Sooden-Allendorf, Germany.
Rüdiger ReerDepartment of Sports Medicine, Institute for Human Movement Science, Faculty for Psychology and Human Movement Science, University of Hamburg, 20148 Hamburg, Germany.
Tobias SchmidtOsteopathic Research Institute, Osteopathie Schule Deutschland, 22297 Hamburg, Germany.
Robert SchleipDepartment for Medical Professions, Diploma Hochschule, 37242 Bad Sooden-Allendorf, Germany.ORCID 0000-0002-1225-0475
Diploma Hochschule · DEUniversität Hamburg · DEMSH Medical School Hamburg – University of Applied Sciences and Medical University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The thoracolumbar fascia (TLF) is thought to play a role in the development of LBP, but it is not yet clear which factor of TLF changes is a cause and which is an effect. Therefore, some studies used the cross-correlation function (CCR) to reveal time-dependent relationships between biomechanical and neuromotor factors. Methods: Ten patients with acute low back pain (aLBP) were matched to healthy controls. Simultaneous recording of surface electromyography (sEMG) of the erector spinae and multifidus muscle (ESM) and dynamic ultrasound (US) images of TLF deformation were performed during trunk extension. CCR functions and Granger causality (GC) were used to describe the relationship between the two measures. Results: CCR time lags were significant higher in the aLBP group (p = 0.04). GC showed a direct effect of TLF deformation on ESM activation only in the aLBP group (p < 0.03). Conclusions: The results suggest that in aLBP, ESM activity is significantly affected by TLF, whereas this relationship is completely random in healthy subjects studied with CCR and GC comparisons of dynamic US imaging and sEMG data signals. Fascia-related disturbances in neuromotor control, particularly due to altered muscle spindle functions, are suspected as a possible mechanism behind this.

Indexed as

EMGerector spinae musclelow back painmultifidus musclemuscle spindlethoracolumbar fasciaultrasound imaging

Identifiers

PMID36362889
PMCPMC9697365
OpenAlexW4307940632

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.