Evidence map›Paper›PMID 36362845›Full record

ArticleLife (Basel, Switzerland)2022

Safety of Electrotherapy Treatment in Patients with Knee Osteoarthritis and Cardiac Diseases.

Laszlo Irsay, Rodica Ana Ungur, Ileana Monica Borda, Irina Tica, Mădălina Gabriela Iliescu, Alina Deniza Ciubean, Theodor Popa, Delia Cinteza, Florina Ligia Popa, Cosmina Ioana Bondor and 1 more

Registry-linked trialAbstract read
In one paragraph

Article in Life (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06451601 (The Metabolic and Respiratory Effects of Intermittent Hypoxia-hyperoxia Therapy in Obese Patients Within the Complex Management of Medical Rehabilitation), which is not on this map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06451601 nacompletednot on this mapstarted 2024, after this paper: background citation

The Metabolic and Respiratory Effects of Intermittent Hypoxia-hyperoxia Therapy in Obese Patients Within the Complex Management of Medical Rehabilitation

TypeinterventionalSponsorBalnear and Rehabilitation Sanatorium TechirghiolRan2024 to 2024Enrolled70ConditionsObesityArmsIntermittent hypoxia-hyperoxia therapy
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Laszlo IrsayDepartment of Rehabilitation Medicine, University of Medicine and Pharmacy, "Iuliu Hatieganu", 8 Victor Babes Street, 400012 Cluj-Napoca, Romania.
Rodica Ana UngurDepartment of Rehabilitation Medicine, University of Medicine and Pharmacy, "Iuliu Hatieganu", 8 Victor Babes Street, 400012 Cluj-Napoca, Romania.ORCID 0000-0001-8095-8937
Ileana Monica BordaDepartment of Rehabilitation Medicine, University of Medicine and Pharmacy, "Iuliu Hatieganu", 8 Victor Babes Street, 400012 Cluj-Napoca, Romania.
Irina TicaFaculty of Medicine, "Ovidius" University of Constanta, 1 University Alley, Campus-Corp B, 900470 Constanta, Romania.
Mădălina Gabriela IliescuFaculty of Medicine, "Ovidius" University of Constanta, 1 University Alley, Campus-Corp B, 900470 Constanta, Romania.ORCID 0000-0002-8573-3160
Alina Deniza CiubeanDepartment of Rehabilitation Medicine, University of Medicine and Pharmacy, "Iuliu Hatieganu", 8 Victor Babes Street, 400012 Cluj-Napoca, Romania.
Theodor PopaDepartment of Rehabilitation Medicine, Clinical Rehabilitation Hospital, 46-50 Viilor Street, 400337 Cluj-Napoca, Romania.
Delia Cinteza9th Department-Physical Medicine and Rehabilitation, "Carol Davila" University of Medicine and Pharmacy, 37 Dionisie Lupu Street, 020021 Bucharest, Romania.
Florina Ligia PopaPhysical Medicine and Rehabilitation Department, Faculty of Medicine, "Lucian Blaga" University of Sibiu, Victoriei Blvd., 550024 Sibiu, Romania.ORCID 0000-0002-9834-3380
Cosmina Ioana BondorDepartment of Medical Informatics and Biostatistics, University of Medicine and Pharmacy, "Iuliu Hatieganu", 6 Pasteur Street, 400349 Cluj-Napoca, Romania.
Viorela Mihaela CiorteaDepartment of Rehabilitation Medicine, University of Medicine and Pharmacy, "Iuliu Hatieganu", 8 Victor Babes Street, 400012 Cluj-Napoca, Romania.ORCID 0000-0001-6402-6443

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the safety of electrotherapy applied in the knee area in patients with known atrial arrhythmias or ischemic heart disease, as it is not known whether this treatment induces or aggravates arrhythmias during or immediately after therapy. MATERIAL AND

methodsThe analytical and transversal study involved 46 patients with degenerative knee osteoarthritis (OA), with or without cardiac diseases, from the Clinical Rehabilitation Hospital inpatient center, Cluj-Napoca, Romania. All patients underwent a 10-day physical therapy program for knee OA (electrotherapy, massage and kinesiotherapy). Heart rate and the total number of ventricular and supraventricular extrasystoles were evaluated before and after treatment, by 24 h Holter ECG monitoring.

resultsThere was no significant increase in heart rate or in the number of ventricular or supraventricular extrasystoles before or after electrotherapy treatment, regardless of the positive or negative history of arrhythmia or ischemic heart disease (all p > 0.05). Mean values during day 1 were: 35.15 (95% CI [9.60−60.75]) for ventricular ones extrasystoles and 91.7 (95% CI [51.69−131.7]) for supraventricular ones, which during day 2 were 38.09 (95% CI [3.68−72.50]), 110.48 (95% CI [48.59−172.36]), respectively.

conclusionOne of the most important things to consider when dealing with an OA patient is that they are most likely older than 65 years, which increases the chance of having a cardiac disease. This raises the need for viable interventions regarding the management of this disease in patients that probably have multiple comorbidities, and where pharmacological and surgical management are not possible, limited or have multiple side effects. Electrotherapy used for treating knee OA did not cause a significant increase in heart rate or number of ventricular and supraventricular extrasystoles in this category of patients.

Indexed as

cardiac arrhythmiacontraindicationselectrotherapyischemic heart diseaseknee osteoarthritis

Identifiers

PMID36362845
PMCPMC9699242

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.