Evidence map›Paper›PMID 36362832›Full record

ArticleLife (Basel, Switzerland)2022

Proteomic Identification of Markers of Membrane Repair, Regeneration and Fibrosis in the Aged and Dystrophic Diaphragm.

Stephen Gargan, Paul Dowling, Margit Zweyer, Michael Henry, Paula Meleady, Dieter Swandulla, Kay Ohlendieck

Open access · goldAbstract read
In one paragraph

Article in Life (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Review
  3. bioRxiv : the preprint server for biology · 2026
    Article
  4. Serum protein biomarker signature of Duchenne muscular dystrophy.European journal of translational myology · 2025
    Article
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  11. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Stephen GarganDepartment of Biology, Maynooth University, National University of Ireland, W23 F2H6 Maynooth, Ireland.
Paul DowlingDepartment of Biology, Maynooth University, National University of Ireland, W23 F2H6 Maynooth, Ireland.
Margit ZweyerDepartment of Neonatology and Paediatric Intensive Care, Children's Hospital, German Center for Neurodegenerative Diseases, University of Bonn, D53127 Bonn, Germany.
Michael HenryNational Institute for Cellular Biotechnology, Dublin City University, D09 E432 Dublin, Ireland.
Paula MeleadyNational Institute for Cellular Biotechnology, Dublin City University, D09 E432 Dublin, Ireland.
Dieter SwandullaInstitute of Physiology, University of Bonn, D53115 Bonn, Germany.ORCID 0000-0003-0923-7090
Kay OhlendieckDepartment of Biology, Maynooth University, National University of Ireland, W23 F2H6 Maynooth, Ireland.ORCID 0000-0002-6266-4510
National University of Ireland, Maynooth · IEDublin City University · IEUniversity of Bonn · DE

Funding

Science Foundation Ireland SFI 16/RI/3701
6 · The paper itself

Abstract

Deficiency in the membrane cytoskeletal protein dystrophin is the underlying cause of the progressive muscle wasting disease named Duchenne muscular dystrophy. In order to detect novel disease marker candidates and confirm the complexity of the pathobiochemical signature of dystrophinopathy, mass spectrometric screening approaches represent ideal tools for comprehensive biomarker discovery studies. In this report, we describe the comparative proteomic analysis of young versus aged diaphragm muscles from wild type versus the dystrophic

Indexed as

annexinbiomarkercollagendegenerationdystrophinopathyfibrosismembrane repairmuscular dystrophyperiostinregeneration

Identifiers

PMID36362832
PMCPMC9696191
OpenAlexW4307262838

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.