Evidence map›Paper›PMID 36362826›Full record

ArticleJournal of clinical medicine2022

Cardiac Troponin I Reveals Diagnostic and Prognostic Superiority to Aminoterminal Pro-B-Type Natriuretic Peptide in Sepsis and Septic Shock.

Jan Forner, Tobias Schupp, Kathrin Weidner, Jonas Rusnak, Schanas Jawhar, Floriana Dulatahu, Lea Marie Brück, Michael Behnes, Ursula Hoffmann, Thomas Bertsch and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Jan FornerFirst Department of Medicine, University Medical Centre Mannheim, Faculty of Medicine Mannheim, Heidelberg University, 61867 Mannheim, Germany.
Tobias SchuppFirst Department of Medicine, University Medical Centre Mannheim, Faculty of Medicine Mannheim, Heidelberg University, 61867 Mannheim, Germany.ORCID 0000-0001-8171-7617
Kathrin WeidnerFirst Department of Medicine, University Medical Centre Mannheim, Faculty of Medicine Mannheim, Heidelberg University, 61867 Mannheim, Germany.
Jonas RusnakFirst Department of Medicine, University Medical Centre Mannheim, Faculty of Medicine Mannheim, Heidelberg University, 61867 Mannheim, Germany.
Schanas JawharFirst Department of Medicine, University Medical Centre Mannheim, Faculty of Medicine Mannheim, Heidelberg University, 61867 Mannheim, Germany.
Floriana DulatahuFirst Department of Medicine, University Medical Centre Mannheim, Faculty of Medicine Mannheim, Heidelberg University, 61867 Mannheim, Germany.
Lea Marie BrückFirst Department of Medicine, University Medical Centre Mannheim, Faculty of Medicine Mannheim, Heidelberg University, 61867 Mannheim, Germany.
Michael BehnesFirst Department of Medicine, University Medical Centre Mannheim, Faculty of Medicine Mannheim, Heidelberg University, 61867 Mannheim, Germany.ORCID 0000-0001-5970-0093
Ursula HoffmannFirst Department of Medicine, University Medical Centre Mannheim, Faculty of Medicine Mannheim, Heidelberg University, 61867 Mannheim, Germany.
Thomas BertschInstitute of Clinical Chemistry, Laboratory Medicine and Transfusion Medicine, Nuremberg General Hospital, Paracelsus Medical University, 90419 Nuremberg, Germany.
Maximilian KittelInstitute for Clinical Chemistry, Faculty of Medicine Mannheim, Heidelberg University, 68167 Mannheim, Germany.ORCID 0000-0002-2580-5038
Ibrahim AkinFirst Department of Medicine, University Medical Centre Mannheim, Faculty of Medicine Mannheim, Heidelberg University, 61867 Mannheim, Germany.
Heidelberg University · DENuremberg Hospital · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Data regarding the prognostic value of cardiac biomarkers in patients suffering from sepsis or septic shock is scarce. Studies investigating the prognostic role of cardiac biomarkers in patients with sepsis and septic shock were commonly published prior to the sepsis-3 criteria and were often not restricted to septic patients only, too. This study investigated the diagnostic and prognostic value of the aminoterminal pro-B-type Natriuretic Peptide (NT-pro BNP) and cardiac troponin I (cTNI) in patients with sepsis and septic shock. Consecutive patients with sepsis and septic shock were included from 2019 to 2021. Blood samples were retrieved from the day of disease onset (i.e., day 1), day 2 and 3. Firstly, the diagnostic value of the NT-pro BNP and cTNI to diagnose sepsis or septic shock was tested. Secondly, the prognostic value of the NT-pro BNP and cTNI was examined with regard to the 30-day all-cause mortality. The statistical analyses included univariable

Indexed as

cTNINT-pro BNPprognosissepsisseptic shock

Identifiers

PMID36362826
PMCPMC9658155
OpenAlexW4308509754

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.