Evidence map›Paper›PMID 36362811›Full record

ArticleJournal of clinical medicine2022

Long-Term Follow-Up of Catheter Ablation for Premature Ventricular Complexes in the Modern Era: The Importance of Localization and Substrate.

Simone Gulletta, Alessio Gasperetti, Marco Schiavone, Gabriele Paglino, Pasquale Vergara, Paolo Compagnucci, Caterina Bisceglia, Manuela Cireddu, Nicolai Fierro, Giuseppe D'Angelo and 7 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 3 pooled it
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 3 syntheses or guidelines pooled it, 16 citations in OpenAlex.

  1. Ventricular pulsed field ablation from bench to bedside: preclinical and clinical evidence from a systematic review and meta-analysis.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 2 countries.

Simone GullettaDepartment of Arrhythmology, San Raffaele Hospital, 20132 Milan, MI, Italy.
Alessio GasperettiCardiology Unit, Luigi Sacco University Hospital, 20157 Milan, MI, Italy.ORCID 0000-0003-3432-070X
Marco SchiavoneCardiology Unit, Luigi Sacco University Hospital, 20157 Milan, MI, Italy.ORCID 0000-0003-0720-3380
Gabriele PaglinoDepartment of Arrhythmology, San Raffaele Hospital, 20132 Milan, MI, Italy.
Pasquale VergaraDepartment of Arrhythmology, San Raffaele Hospital, 20132 Milan, MI, Italy.
Paolo CompagnucciCardiology and Arrhythmology Clinic, University Hospital Umberto-I-Salesi-Lancisi, 60123 Ancona, AN, Italy.ORCID 0000-0003-1924-6548
Caterina BiscegliaDepartment of Arrhythmology, San Raffaele Hospital, 20132 Milan, MI, Italy.
Manuela CiredduDepartment of Arrhythmology, San Raffaele Hospital, 20132 Milan, MI, Italy.
Nicolai FierroDepartment of Arrhythmology, San Raffaele Hospital, 20132 Milan, MI, Italy.
Giuseppe D'AngeloDepartment of Arrhythmology, San Raffaele Hospital, 20132 Milan, MI, Italy.ORCID 0000-0002-1198-9745
Simone SalaDepartment of Arrhythmology, San Raffaele Hospital, 20132 Milan, MI, Italy.ORCID 0000-0003-3303-8892
Lorenzo RampaDepartment of Arrhythmology, San Raffaele Hospital, 20132 Milan, MI, Italy.
Michela CasellaCardiology and Arrhythmology Clinic, University Hospital Umberto-I-Salesi-Lancisi, 60123 Ancona, AN, Italy.ORCID 0000-0002-5322-1742
Patrizio MazzoneDepartment of Arrhythmology, San Raffaele Hospital, 20132 Milan, MI, Italy.
Antonio Dello RussoCardiology and Arrhythmology Clinic, University Hospital Umberto-I-Salesi-Lancisi, 60123 Ancona, AN, Italy.
Giovanni Battista ForleoCardiology Unit, Luigi Sacco University Hospital, 20157 Milan, MI, Italy.ORCID 0000-0001-8895-8915
Paolo Della BellaDepartment of Arrhythmology, San Raffaele Hospital, 20132 Milan, MI, Italy.
Ospedali Riuniti Umberto I · ITJohns Hopkins University · USLuigi Sacco Hospital · ITUniversity of Rome Tor Vergata · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Large-scale studies evaluating long-term recurrence rates in both idiopathic and non-idiopathic PVC catheter ablation (CA) patients have not been reported. Objective: To evaluate the efficacy and safety of idiopathic and non-idiopathic PVC CA, investigating the predictors of acute and long-term efficacy. Methods: This retrospective multicentric study included 439 patients who underwent PVC CA at three institutions from April-2015 to December-2021. Clinical success at 6 months’ follow-up, defined as a reduction of at least 80% of the pre-procedural PVC burden, was deemed the primary outcome. The secondary aims of the study were: clinical success at the last available follow-up, predictors of arrhythmic recurrences at long-term follow-up, and safety outcomes. Results: The median age was 51 years, with 24.9% patients being affected suffering from structural heart disease. The median pre-procedural PVC burden was 20.1%. PVCs originating from the RVOT were the most common index PVC observed (29.1%), followed by coronary cusp (CC) and non-outflow tract (OT) LV PVCs (23.1% and 19.0%). The primary outcome at 6 months was reached in 85.1% cases, with a significant reduction in the 24 h% PVC burden (−91.4% [−83.4; −96.7], p < 0.001); long-term efficacy was observed in 82.1% of cases at almost 3-year follow-up. The presence of underlying structural heart disease and non-OT LV region origin (aHR 1.77 [1.07−2.93], p = 0.027 and aHR = 1.96 [1.22−3.14], p = 0.005) was independently associated with recurrences. Conclusion: CA of both idiopathic and non-idiopathic PVCs showed a very good acute and long-term procedural success rate, with an overall low complication. Predictors of arrhythmic recurrence at follow-up were underlying structural heart disease and non-OT LV origin.

Indexed as

arrhythmic recurrencescatheter ablationclinical outcomescomplicationspremature ventricular complexes

Identifiers

PMID36362811
PMCPMC9654324
OpenAlexW4308531520

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.