Evidence map›Paper›PMID 36362809›Full record

ArticleJournal of clinical medicine2022

Impact of the COVID-19 Pandemic on Solid Organ Transplant and Rejection Episodes in Brazil's Unified Healthcare System.

Luis Gustavo Modelli de Andrade, Abner Macola Pacheco Barbosa, Naila Camila da Rocha, Marilia Mastrocolla de Almeida Cardoso, Juliana Tereza Coneglian de Almeida, Juliana Machado-Rugolo, Lucas Frederico Arantes, Daniela Ferreira Salomão Pontes, Gustavo Fernandes Ferreira

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Dialysis Requirements of Kidney Transplant Recipients During COVID-19.Journal of clinical practice and research · 2023
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Luis Gustavo Modelli de AndradeDepartment of Internal Medicine-UNESP, Univ Estadual Paulista, Av. Prof. Montenegro-Distrito de, Rubião Jr., s/n, Botucatu 18618-687, SP, Brazil.ORCID 0000-0002-0230-0766
Abner Macola Pacheco BarbosaDepartment of Internal Medicine-UNESP, Univ Estadual Paulista, Av. Prof. Montenegro-Distrito de, Rubião Jr., s/n, Botucatu 18618-687, SP, Brazil.ORCID 0000-0003-3668-8911
Naila Camila da RochaDepartment of Internal Medicine-UNESP, Univ Estadual Paulista, Av. Prof. Montenegro-Distrito de, Rubião Jr., s/n, Botucatu 18618-687, SP, Brazil.ORCID 0000-0002-1684-2574
Marilia Mastrocolla de Almeida CardosoHealth Technology Assessment Center Hospital das Clínicas-HCFMB, Botucatu 18618-970, SP, Brazil.ORCID 0000-0002-6231-5425
Juliana Tereza Coneglian de AlmeidaHealth Technology Assessment Center Hospital das Clínicas-HCFMB, Botucatu 18618-970, SP, Brazil.ORCID 0000-0001-8865-0398
Juliana Machado-RugoloHealth Technology Assessment Center Hospital das Clínicas-HCFMB, Botucatu 18618-970, SP, Brazil.ORCID 0000-0003-3984-4959
Lucas Frederico ArantesHealth Technology Assessment Center Hospital das Clínicas-HCFMB, Botucatu 18618-970, SP, Brazil.ORCID 0000-0002-4946-5189
Daniela Ferreira Salomão PontesDepartment of Internal Medicine-UNESP, Univ Estadual Paulista, Av. Prof. Montenegro-Distrito de, Rubião Jr., s/n, Botucatu 18618-687, SP, Brazil.ORCID 0000-0001-7171-771X
Gustavo Fernandes FerreiraTransplant Unit-Santa Casa Juiz de Fora, Av. Barão do Rio Branco, 3353-Passos, Juiz de Fora 36021-630, MG, Brazil.ORCID 0000-0002-0036-0298

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBrazil has the world's largest public organ transplant program, which was severely affected by the COVID-19 pandemic. The primary aim of the study was to evaluate differences in solid organ transplants and rejection episodes during the COVID-19 pandemic compared to the five years before the pandemic in the country.

methodsA seven-year database was built by downloading data from the DATASUS server. The pandemic period was defined as March 2020 to December 2021. The pre-pandemic period was from January 2015 to March 2020.

resultsDuring the pandemic, the number of solid organ transplants decreased by 19.3% in 2020 and 22.6% in 2021 compared to 2019. We found a decrease for each evaluated organ, which was more pronounced for lung, pancreas, and kidney transplants. The seasonal plot of rejection data indicated a high rejection rate between 2018 and 2021. There was also an 18% (IRR 1.18 (95% CI 1.01 to 1.37),

conclusionsThe total number of organ transplants performed in 2021 represents a setback of six years. Transplant procedures were concentrated in the Southeast region of the country, and a higher proportion of rejections occurred during the pandemic. Together, these findings could have an impact on transplant procedures and outcomes in Brazil.

Indexed as

BrazilCOVID-19graft rejectionorgan transplant

Identifiers

PMID36362809
PMCPMC9658443

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.