ArticleJournal of clinical medicine2022
Magnetic Resonance-Guided Laser Interstitial Thermal Therapy for Hypothalamic Hamartoma: Surgical Approach and Treatment Outcomes.
Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 15 citations in OpenAlex.
- Pediatric endocrine disorders: a review of intracranial findings and appropriate imaging.Pediatric radiology · 2026Review
- Robotic Surgery in Pediatric Epilepsy : Current Evidence, Clinical Impact, and Future Directions.Journal of Korean Neurosurgical Society · 2026Article
- Epilepsy: Molecular Pathogenesis and Emerging Therapies.MedComm · 2026Review
- Robot-assisted MRI-guided laser interstitial thermal therapy for a giant sessile hypothalamic hamartoma in an 8-year-old boy: illustrative case.Journal of neurosurgery. Case lessons · 2025Article
- Laser interstitial thermal therapy for hypothalamic-hamartoma-related epilepsy: the long-term cognitive outcome of the first pediatric case in Europe.Acta neurochirurgica · 2024Article
- Surgical and radiosurgical treatment of hypothalamic hamartoma: The Italian experience between 2011 and 2021.Epilepsia open · 2024Article
- Direct resection is a safe and effective strategy to control seizures in patients with hypothalamic hamartoma.Scientific reports · 2024Article
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Authors and funding
12 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hypothalamic hamartoma (HH) is a rare lesion consisting of normal neurons and neuroglia arranged in an abnormal pattern which usually causes gelastic seizures (GS). Magnetic resonance-guided laser interstitial thermal therapy (MRgLITT) has been developed as a minimally invasive approach to treat HH and gradually become a first-line treatment. In total, this study enrolled 47 consecutive HH patients that underwent one round of ablation. Patients were followed for at least one year. Patients' medical records and surgical information were carefully reviewed, and univariate analyses were performed. Of the treated patients, 72.3% remained GS-free in this study, with an overall Engel class I rate of 68.1%. Long-term postoperative complications occurred in six patients. Factors associated with GS prognosis included Delalande classification (
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