Evidence map›Paper›PMID 36362781›Full record

ArticleJournal of clinical medicine2022

Digital Twins in Radiology.

Filippo Pesapane, Anna Rotili, Silvia Penco, Luca Nicosia, Enrico Cassano

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. The Role of AI in Clinical Trial Design and Scientific Writing.Cardiovascular and interventional radiology · 2026
    Review
  3. Digital Twin Technology In Radiology.Journal of imaging informatics in medicine · 2026
    Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Patient-centered modeling of the breast biopsy experience.Frontiers in artificial intelligence · 2025
    Article
  12. Review
  13. Article
  14. Digital twins: a new paradigm in oncology in the era of big data.ESMO real world data and digital oncology · 2024
    Review
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Filippo PesapaneBreast Imaging Division, IEO European Institute of Oncology IRCCS, 20141 Milan, Italy.ORCID 0000-0002-0374-5054
Anna RotiliBreast Imaging Division, IEO European Institute of Oncology IRCCS, 20141 Milan, Italy.ORCID 0000-0001-9439-9275
Silvia PencoBreast Imaging Division, IEO European Institute of Oncology IRCCS, 20141 Milan, Italy.
Luca NicosiaBreast Imaging Division, IEO European Institute of Oncology IRCCS, 20141 Milan, Italy.ORCID 0000-0003-3979-8075
Enrico CassanoBreast Imaging Division, IEO European Institute of Oncology IRCCS, 20141 Milan, Italy.ORCID 0000-0002-3437-8939

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A digital twin is a virtual model developed to accurately reflect a physical thing or a system. In radiology, a digital twin of a radiological device enables developers to test its characteristics, make alterations to the design or materials, and test the success or failure of the modifications in a virtual environment. Innovative technologies, such as AI and -omics sciences, may build virtual models for patients that are continuously adjustable based on live-tracked health/lifestyle parameters. Accordingly, healthcare could use digital twins to improve personalized medicine. Furthermore, the accumulation of digital twin models from real-world deployments will enable large cohorts of digital patients that may be used for virtual clinical trials and population studies. Through their further refinement, development, and application into clinical practice, digital twins could be crucial in the era of personalized medicine, revolutionizing how diseases are detected and managed. Although significant challenges remain in the development of digital twins, a structural modification to the current operating models is occurring, and radiologists can guide the introduction of such technology into healthcare.

Indexed as

artificial intelligencedigital devicesdigital patientsdigital twinspersonalized medicine

Identifiers

PMID36362781
PMCPMC9655926

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.