ArticleJournal of clinical medicine2022
The Association between Serum Albumin and Post-Operative Outcomes among Patients Undergoing Common Surgical Procedures: An Analysis of a Multi-Specialty Surgical Cohort from the National Surgical Quality Improvement Program (NSQIP).
Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
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Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.
- Predictors of Complications and Recurrence After Pressure Injury Reconstruction in Spinal Cord Injury: A Systematic Review and Meta-Analysis.International wound journal · 2026Pooled it
- Pooled it
- Article
- Cerebral Palsy and Postoperative Outcomes After Distal Radius Fracture Repair: A Retrospective Analysis.Journal of hand surgery global online · 2026Article
- Preoperative Glucose-to-Albumin Ratio as a Prognostic Marker for Survival in Pancreatic Cancer Patients Undergoing Pancreatectomy.Cancer medicine · 2026Article
- Development of the Novel G-CMAP Score: A Preoperative Scoring System for Predicting Postoperative Complications After Gastrectomy for Gastric Cancer.Annals of surgical oncology · 2026Article
- The impact of preoperative nutritional status on 30-day outcomes after elective lumbar laminectomy for lumbar stenosis: a population-based cohort analysis.Asian spine journal · 2026Article
- Clinical risk factors for multidrug-resistant organism infections in postoperative gastric cancer patients: an ICU-based retrospective analysis.BMC infectious diseases · 2026Article
- Association between lactate-to-albumin ratio and clinical outcomes in perioperative patients with chronic kidney disease: a retrospective cohort study based on INSPIRE database.Clinical and experimental nephrology · 2026Article
- Preoperative nutritional risk and adverse perioperative outcomes in children with congenital choledochal cysts: a retrospective cohort study.Frontiers in pediatrics · 2026Article
- Baseline Serum Albumin for Long-Term Risk Stratification in Maintenance Hemodialysis Patients: A Retrospective Cohort Study.Journal of clinical medicine · 2026Article
- Bidirectional Relationship Between Systemic Immune-Inflammation Index and Postoperative Pneumonia in Elderly Patients Undergoing Colorectal Cancer Surgery: A Retrospective Cohort Study.Clinical interventions in aging · 2026Article
- Essential Amino Acid Supplementation May Attenuate Systemic Inflammation and Improve Hypoalbuminemia in Subacute Hemiplegic Stroke Patients.Metabolites · 2025Article
- Article
- Frailty and malnutrition scores in predicting postoperative complications in minimally invasive prostatectomy for malignancy of the prostate.Journal of robotic surgery · 2025Article
- Incidence and risk factors of postpartum urinary retention following cesarean section: a retrospective nationwide inpatient sample database study.BMC women's health · 2025Article
- Review
- Correlation between preoperative systemic immune inflammation index, nutritional risk index, and prognosis of radical resection of liver cancer.World journal of gastrointestinal surgery · 2023Article
- Prediction of major postoperative events after non-cardiac surgery for people with kidney failure: derivation and internal validation of risk models.BMC nephrology · 2023Article
- Racial Disparities in Outcomes of Bariatric Surgery: An Analysis of 190,319 Patients.JSLS : Journal of the Society of Laparoendoscopic SurgeonsArticle
Corrections and comments
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Authors and funding
13 authors at 5 institutions in 2 countries.
Funding
Abstract
While studies have demonstrated an association between preoperative hypoalbuminemia and adverse clinical outcomes, the optimal serum albumin threshold for risk-stratification in the broader surgical population remains poorly defined. We sought define the optimal threshold of preoperative serum albumin concentration for risk-stratification of adverse post-operative outcomes. Using the American College of Surgeons National Surgical Quality Improvement Program Database, we identified 842,672 patients that had undergone a common surgical procedure in one of eight surgical specialties. An optimal serum albumin concentration threshold for risk-stratification was determined using receiver-operating characteristic analysis. Multivariable logistic regression analysis was used to evaluate the odds of adverse surgical events; a priori defined subgroup analyses were performed. A serum albumin threshold of 3.4 g/dL optimally predicted adverse surgical outcomes in the broader cohort. After multivariable analysis, patients with hypoalbuminemia had increased odds of death within 30 days of surgery (odds ratio [OR] 2.01, 95% confidence interval [CI] 1.94-2.08). Hypoalbuminemia was associated with greater odds of primary adverse events among patients with disseminated cancer (OR 2.03, 95% CI 1.88-2.20) compared to patients without disseminated cancer (OR 1.47, 95% CI 1.44-1.51). The standard clinical threshold for hypoalbuminemia is the optimal threshold for preoperative risk assessment.
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