Evidence map›Paper›PMID 36362761›Full record

ReviewJournal of clinical medicine2022

Multicentric Reticulohistiocytosis Associated with an Early Form of Systemic Lupus Erythematosus: A Case Report of a Rare Disease, with Mini Review of the Literature.

Elena Biancamaria Mariotti, Alberto Corrà, Elisa Lemmi, Lucrezia Laschi, Cristina Aimo, Lavinia Quintarelli, Walter Volpi, Francesca Nacci, Alice Verdelli, Valentina Ruffo di Calabria and 2 more

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Elena Biancamaria MariottiSection of Dermatology, Department of Health Sciences, University of Florence, 50125 Florence, Italy.ORCID 0000-0003-0388-1037
Alberto CorràSection of Dermatology, Department of Health Sciences, University of Florence, 50125 Florence, Italy.ORCID 0000-0003-0903-4998
Elisa LemmiSection of Anatomical Pathology, Department of Health Sciences, University of Florence, 50125 Florence, Italy.
Lucrezia LaschiSection of Anatomical Pathology, Department of Health Sciences, University of Florence, 50125 Florence, Italy.
Cristina AimoSection of Dermatology, Department of Health Sciences, University of Florence, 50125 Florence, Italy.
Lavinia QuintarelliRare Disease Skin Unit, Section of Dermatology, Azienda USL Toscana Centro, University of Florence, 50125 Florence, Italy.
Walter VolpiSection of Dermatology, Azienda USL Toscana Centro, 50125 Florence, Italy.
Francesca NacciSection of Rheumatology, Department of Clinical and Experimental Medicine, University of Florence, 50125 Florence, Italy.
Alice VerdelliSection of Dermatology, Azienda USL Toscana Centro, 50125 Florence, Italy.
Valentina Ruffo di CalabriaSection of Dermatology, Department of Health Sciences, University of Florence, 50125 Florence, Italy.ORCID 0000-0003-0307-6636
Serena GuiducciSection of Rheumatology, Department of Clinical and Experimental Medicine, University of Florence, 50125 Florence, Italy.
Marzia CaproniRare Disease Skin Unit, Section of Dermatology, Azienda USL Toscana Centro, University of Florence, 50125 Florence, Italy.ORCID 0000-0002-7471-3471
University of Florence · ITAzienda Usl Toscana Centro · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multicentric reticulohistiocytosis (MRH) is the most frequently described form of reticulohistiocytosis (RH), and it is classified as a class IIb non-Langerhans cell histiocytosis. It has been designated as multicentric, being characterized by multisystemic involvement. In fact, although mainly involving the skin, along with the joints, it is a systemic inflammatory condition potentially involving every internal organ. As MRH-related skin findings can mimic rheumatoid nodules or Gottron papules, the histopathology of the cutaneous lesions is often necessary for the correct diagnosis. Approximately one-third of MRH patients have confirmed concomitant autoimmune disorders. A wide variety of autoimmune disorders associated with the disease have been reported in the literature, suggesting immune dysfunction as a factor in the pathophysiology of MRH. A case of MRH associated with autoimmune manifestation is reported in the context of a mini review of the literature, with a focus on clinical presentation, treatments, and treatment outcomes. Moreover, eight cases of MRH associated with autoimmune diseases are briefly discussed.

Indexed as

autoimmune diseasecase reportmulticentric reticulohistiocytosis

Identifiers

PMID36362761
PMCPMC9658768
OpenAlexW4308352068

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.