ReviewJournal of clinical medicine2022
The Roles of Vitamins in Diabetic Retinopathy: A Narrative Review.
Review in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
21 citing papers in PubMed, 27 citations in OpenAlex.
- Comparative analysis of activation of macrophages/microglia in diabetic retinopathy and Familial Exudative Vitreoretinopathy.Biochemistry and biophysics reports · 2026Article
- The linear association between vitamin B12 and diabetic retinopathy in type 2 diabetic patients: a cross-sectional study.Frontiers in medicine · 2026Article
- Serum 25-hydroxyvitamin D levels and prevalent diabetic retinopathy in adults with type 2 diabetes: a retrospective hospital-based matched case-control study.Frontiers in nutrition · 2026Article
- Association Between Serum Vitamin D3 Levels and Diabetic Macular Edema in Patients with Type 2 Diabetes: A Retrospective Case-Control Study.Diabetes, metabolic syndrome and obesity : targets and therapy · 2026Article
- B Vitamins and Ocular Health.Clinical ophthalmology (Auckland, N.Z.) · 2026Review
- Effect ofLife (Basel, Switzerland) · 2025Article
- Restoring Glutathione Homeostasis in Glycation-Related Eye Diseases: Mechanistic Insights and Therapeutic Interventions Beyond VEGF Inhibition.Antioxidants (Basel, Switzerland) · 2025Review
- Diabetic Macular Edema in Maintenance Intravitreal Scheduling.Pharmaceutics · 2025Article
- Novel Therapeutic Approaches for Treatment of Diabetic Retinopathy and Age-Related Macular Degeneration.Vision (Basel, Switzerland) · 2025Review
- Exploring the association between composite dietary antioxidant index and ocular diseases: a cross-sectional study.BMC public health · 2025Article
- Association Between Low Serum Vitamin A Level and Diabetic Retinopathy in Patients with Type 2 Diabetes: A Hospital-Based Study.Journal of inflammation research · 2025Article
- The Role of Diet and Oral Supplementation for the Management of Diabetic Retinopathy and Diabetic Macular Edema: A Narrative Review.BioMed research international · 2025Review
- The use of vitamin E in ocular health: Bridging omics approaches with Tocopherol and Tocotrienol in the management of glaucoma.Food chemistry. Molecular sciences · 2024Article
- Effect of High-Sucrose Diet on the Occurrence and Progression of Diabetic Retinopathy and Dietary Modification Strategies.Nutrients · 2024Review
- The relationship between blood vitamin A levels and diabetic retinopathy: a population-based study.Scientific reports · 2024Article
- Correction of presbyopia using 0.5% pilocarpine eye drops among Indians.Bioinformation · 2024Article
- Mediation of endothelial activation and stress index in the association between vitamin BFrontiers in nutrition · 2024Article
- Causal effect of immune cells, metabolites, cathepsins, and vitamin therapy in diabetic retinopathy: a Mendelian randomization and cross-sectional study.Frontiers in immunology · 2024Article
- Higher vitamin BFrontiers in nutrition · 2024Article
- Review
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There have been attempts to evaluate the roles of vitamins for the prevention or treatment of eye conditions, such as glaucoma, age-related macular degeneration, and diabetic retinopathy (DR). Regarding DR, two main groups of studies can be identified. The first group focuses on the association between serum levels of an individual vitamin and DR. Many studies have found that lower serum levels of vitamins, particularly vitamin D, are significantly associated with the development, or severity, of DR, while some studies have not supported this trend. The second group evaluates dietary vitamin intakes and DR. A small, randomized placebo-controlled trial did not show any benefit of vitamin E intake on improving the area of retinal hemorrhage or diabetic macular edema at 12 months. A pilot study of patients with mild-to-moderate non-proliferative DR received tablets of combined vitamins B6, B9, and B12 for 6 months and significant improvement in retinal sensitivity and retinal thickness resulted. Two large prospective cohorts showed that high dietary intake of vitamin B6, and fruit rich in vitamin C and E, could significantly lower the risk of DR by 50% after an eight-year follow-up. Properly designed, randomized controlled trials are needed to support the results.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.