ReviewJournal of clinical medicine2022
Multimodal Pain Management in Orthopedic Surgery.
Review in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06701175 (Anterolateral Geniculate Nerve Block and Portal Anesthesia in Knee Arthroscopy for Pain Control), which is not on this map. Cited by 28 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Anterolateral Geniculate Nerve Block and Portal Anesthesia in Knee Arthroscopy for Pain Control: A Randomized Control Trial
Who cites it
28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 50 citations in OpenAlex.
- Brachial Plexus Blockage versus General Anesthesia for Upper Extremity Surgery: A Systematic Review and Meta-Analysis.European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes · 2026Pooled it
- Effectiveness of gabapentinoids in orthopedic surgeries: a systematic review and meta-analysis of postoperative pain, and opioid-sparing effects.BMC anesthesiology · 2025Pooled it
- Quadratus lumborum block versus femoral nerve block in total hip arthroplasty: a randomized clinical trial.BMC anesthesiology · 2026Trial
- Trial
- Pericapsular nerve group block combined with lateral femoral cutaneous nerve blockThe Korean journal of pain · 2026Article
- Retrograde drain-based analgesic cocktail injection for pain control and early mobilization after total knee arthroplasty: a prospective observational study.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2026Observational
- Central Sensitisation After Orthopaedic Trauma: An Overlooked Contributor to Chronic Pain and Functional Disability-A Scoping Review.Journal of clinical medicine · 2026Review
- Potential role for immune cell signatures as predictors of acute and chronic pain in adolescents post major musculoskeletal surgery.Brain, behavior, and immunity · 2026Observational
- Preoperative Beta and Gamma EEG Spectral Power as Independent Predictors of Acute Postoperative Pain in Spinal Surgery: A Prospective Observational Cohort Study.Journal of pain research · 2026Article
- Cross-Cultural Adaptation and Validation for Central Aspects of Pain in the Knee Questionnaire: Based on Chinese Patients Undergoing Total Knee Arthroplasty for Knee Osteoarthritis.Journal of pain research · 2026Article
- Intraoperative pain management for patients undergoing medication-assisted rehabilitation: a scoping review.BMC anesthesiology · 2025Article
- Factors influencing patient satisfaction in postoperative pain management: A systematic review and meta-analysis.Indian journal of anaesthesia · 2025Article
- Medical and recreational cannabis use in patients undergoing one- or two-level lumbar spine fusion correlated with postoperative outcomes.North American Spine Society journal · 2025Article
- Integrating Peripheral Nerve Blocks in Multiple Trauma Care: Current Evidence and Clinical Challenges.Journal of clinical medicine · 2025Review
- Advancing perioperative care: introducing patient-centered comfort management.Gland surgery · 2025Review
- Integrative review of the gut microbiome's role in pain management for orthopaedic conditions.World journal of experimental medicine · 2025Review
- Analgesia Nociception Index Monitoring in Management of Perioperative Analgesia in Total Knee Arthroplasty Surgeries with Femoral Nerve Block.Medicina (Kaunas, Lithuania) · 2025Article
- An update on regional anesthesia in shoulder surgery: a narrative review.Annals of joint · 2025Review
- Transdermal Fentanyl Patch Effectiveness in Postoperative PainManagement in Orthopedic Patients: Literature Review.Journal of clinical medicine · 2024Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOrthopedic surgery typically results in moderate to severe pain in a majority of patients. Opioids were traditionally the primary medication to target mechanisms of pain transmission. Multimodal analgesia has become a preferred method of pain management in orthopedic practice. Utilizing more than one mode to address post-surgical pain by recruiting multiple receptors through different medications accelerates the recovery process and decreases the need for opioids. By implementing effective analgesic techniques and interventions, this practice, in turn, decreases the usage of perioperative opioids, and in the long term, prevents addiction to pain medications and risk of opioid overdose. In orthopedic surgeries, previous studies have found that multimodal analgesia has reduced early opioid usage in the postoperative course. Pain is the result of direct injury to the nervous system, with a wide variety of chemicals directly stimulating or sensitizing the peripheral nociceptors. The pathophysiology behind the mechanism of post-surgical pain, along with the importance of preoperative, perioperative, and postoperative pain regimens are emphasized. A brief overview of pain medications and their properties is provided. These medications are further categorized, with information on special considerations and typical dosage requirements. Pain management should address both neuropathic and subjective types of pain. Effective pain control requires constant reassessment with individualized strategies.
conclusionBy focusing on multimodal analgesia, anesthesiologists can now utilize newer techniques for postoperative pain relief from orthopedic surgery, with better short-term and long-term outcomes for the patient.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.