ReviewJournal of clinical medicine2022
Update on Findings about Sudden Sensorineural Hearing Loss and Insight into Its Pathogenesis.
Review in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.
- Pooled it
- Association between modifiable lifestyle factors and the incidences of sudden sensorineural hearing loss and Meniere's disease: A population-based nested case-control study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Article
- Cat-Scratch Disease Associated with Acute Hearing Loss, Israel.Emerging infectious diseases · 2026Article
- Artificial Intelligence-Assisted Inner Ear Computed Tomography Analysis: Radiomics-Based Comparison of Affected and Unaffected Ears in Idiopathic Sudden Sensorineural Hearing Loss.Journal of imaging informatics in medicine · 2026Article
- Study on the relationship between coagulation function, homocysteine, serum oxidative stress and sudden deafness and its clinical implications.Scientific reports · 2026Article
- Environmental exposure to air pollution and climate: Intersecting the impact on ear and nose health and chemosensory function (Review).International journal of molecular medicine · 2026Review
- SARS-CoV-2 infection and profound hearing loss: much more than a coincidence.Einstein (Sao Paulo, Brazil) · 2026Article
- Multimodal biomarkers in idiopathic sudden sensorineural hearing loss: integrating immune, vascular, and metabolic perspectives for precision medicine.Frontiers in immunology · 2026Review
- Vitamin D Deficiency as a Risk Factor for Onset and Recurrence of Sudden Sensorineural Hearing Loss: A Prospective Cohort Study With Age-Specific Analysis.Food science & nutrition · 2026Article
- PLGA nanoparticles in otoprotection and inner ear regeneration: a new frontier in nanomedicine for hearing disorders.RSC advances · 2025Review
- Comparison of Audiometric Outcomes Following Acute Labyrinthitis.Medicina (Kaunas, Lithuania) · 2025Article
- Comprehensive analysis of aberrant alternative splicing and RNA binding proteins associated with age-related sensorineural hearing loss.Scientific reports · 2025Article
- Utility of Prognostic Nutritional Index and Systemic Immune-Inflammation Index Inpatients With Sudden Sensorineural Hearing Loss: A Large Prospective Cohort Study.Immunity, inflammation and disease · 2025Article
- Therapeutic effectiveness of intratympanic and retroauricular methylprednisolone sodium succinate for refractory sudden sensorineural hearing loss in diabetic patients.World journal of diabetes · 2025Article
- The role of serun lipid, cytokine production in sudden sensorineural hearing loss.Cytotechnology · 2025Article
- Risk of Sudden Sensorineural Hearing Loss in Patients with Gout: A Population-Level Study in a South Korean National Health Screening Cohort.Journal of clinical medicine · 2025Article
- Association Between High Jugular Bulb and Sudden Sensorineural Hearing Loss: A Computed Tomography Based Study.International journal of general medicine · 2025Article
- Disrupted Cross-Scale Network Associated With Cognitive-Emotional Disorders in Sudden Sensorineural Hearing Loss.CNS neuroscience & therapeutics · 2025Article
- Genetic Associations Between Specific Sleep-Related Phenotypes and Idiopathic Sudden Sensorineural Hearing Loss: A Mendelian Randomization Analysis.Nature and science of sleep · 2025Article
- The Predictive Value of NLR, PLR and SII for SSNHL in Children and Young Adults.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
Sudden sensorineural hearing loss (SSNHL) is routinely encountered and is one of the most common emergent diseases in otolaryngology clinics. However, the etiology of SSNHL remains unclear. Due to the inaccessibility of the living human inner ear for biopsy, studies investigating the etiology of SSNHL have been performed by analyzing data obtained from examinations using peripheral blood or imaging. We updated the findings obtained from serological, magnetic resonance imaging, genetic, and viral examinations to reveal the etiology of SSNHL. Regarding viral examination, we focused on sensorineural hearing loss associated with coronavirus disease (COVID-19) because the number of correlated reports has been increasing after the outbreak. The updated findings revealed the following three possible mechanisms underlying the development of SSNHL: thrombosis and resulting vascular obstruction in the cochlea, asymptomatic viral infection and resulting damage to the cochlea, and cochlear inflammation and resulting damage to the cochlea. Thrombosis and viral infection are predominant, and cochlear inflammation can be secondarily induced through viral infection or even thrombosis. The findings about sensorineural hearing loss associated with COVID-19 supported the possibility that asymptomatic viral infection is one of the etiologies of SSNHL, and the virus can infect inner ear tissues and directly damage them.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.