Evidence map›Paper›PMID 36362488›Full record

ArticleJournal of clinical medicine2022

Prognostic Utility of the Modified Glasgow Prognostic Score in Urothelial Carcinoma: Outcomes from a Pooled Analysis.

Daqing Tan, Jinze Li, Tianhai Lin, Ping Tan, Jiapeng Zhang, Qiao Xiong, Jinjiang Jiang, Yifan Li, Peng Zhang, Qiang Wei

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Daqing TanDepartment of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu 610041, China.
Jinze LiDepartment of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu 610041, China.
Tianhai LinDepartment of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu 610041, China.ORCID 0000-0003-0954-3282
Ping TanDepartment of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu 610041, China.
Jiapeng ZhangDepartment of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu 610041, China.
Qiao XiongDepartment of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu 610041, China.
Jinjiang JiangDepartment of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu 610041, China.
Yifan LiDepartment of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu 610041, China.
Peng ZhangDepartment of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu 610041, China.
Qiang WeiDepartment of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu 610041, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Many studies explored the prognostic value of the modified Glasgow Prognostic Score (mGPS) in urothelial carcinoma (UC), but the results are controversial. This study aimed to quantify the relationship between pretreatment mGPS and survival in patients with UC. Methods: A systematic literature search was conducted using Embase, PubMed, and Web of Science to identify eligible studies published before August 2022. Pooled hazard ratios (HRs) with 95% confidence intervals (CIs) were used to assess the association between pretreatment mGPS and the prognosis of UC. Results: Thirteen eligible studies involving 12,524 patients were included. A high mGPS was significantly associated with poor overall survival (mGPS 1/0: HR = 1.33, 95% CI 1.12−1.58, p = 0.001; mGPS 2/0: HR = 2.02, 95% CI 1.43−2.84, p < 0.0001), progression-free survival (mGPS 1/0: HR = 1.26, 95% CI 1.03−1.53, p = 0.021; mGPS 2/0: HR = 1.76, 95% CI 1.12−2.77, p = 0.013), recurrence-free survival (mGPS 1/0: HR = 1.36, 95% CI 1.18−1.56, p < 0.0001; mGPS 2/0: HR = 1.70, 95% CI 1.44−2.000, p < 0.0001), and cancer-specific survival (mGPS 2/0: HR = 1.81, 95% CI 1.30−2.52, p < 0.0001). A subgroup analysis of OS also yielded similar results. Conclusions: Evidence suggests that high pretreatment mGPS in UC is closely related to poor survival. Pre-treatment mGPS is a powerful independent prognostic factor in patients with UC.

Indexed as

meta-analysismodified Glasgow Prognostic Scoreprognosissurvivalurothelial carcinoma

Identifiers

PMID36362488
PMCPMC9655933

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.