Evidence map›Paper›PMID 36362406›Full record

ReviewInternational journal of molecular sciences2022

Regulation of the Key Epithelial Cancer Suppressor miR-124 Function by Competing Endogenous RNAs.

Eleonora A Braga, Marina V Fridman, Alexey M Burdennyy, Elena A Filippova, Vitaly I Loginov, Irina V Pronina, Alexey A Dmitriev, Nikolay E Kushlinskii

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Review
  3. Epigenetic regulation of EZH2 by ncRNAs: mechanisms and oncogenic implications.Naunyn-Schmiedeberg's archives of pharmacology · 2026
    Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Therapeutic Strategies for Angiogenesis Based on Endothelial Cell Epigenetics.Journal of cardiovascular translational research · 2024
    Review
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Eleonora A BragaInstitute of General Pathology and Pathophysiology, 125315 Moscow, Russia.ORCID 0000-0001-5188-4094
Marina V FridmanVavilov Institute of General Genetics, Russian Academy of Sciences, 119991 Moscow, Russia.
Alexey M BurdennyyInstitute of General Pathology and Pathophysiology, 125315 Moscow, Russia.ORCID 0000-0002-9398-8075
Elena A FilippovaInstitute of General Pathology and Pathophysiology, 125315 Moscow, Russia.
Vitaly I LoginovInstitute of General Pathology and Pathophysiology, 125315 Moscow, Russia.
Irina V ProninaInstitute of General Pathology and Pathophysiology, 125315 Moscow, Russia.ORCID 0000-0002-0423-7801
Alexey A DmitrievEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.ORCID 0000-0002-6827-9584
Nikolay E KushlinskiiN.N. Blokhin National Medical Research Center of Oncology, 115478 Moscow, Russia.
Research Institute of General Pathology and Pathophysiology, the Russian Academy of Medical Sciences · RUResearch Centre for Medical Genetics · RUEngelhardt Institute of Molecular Biology · RUVavilov Institute of General Genetics · RU

Funding

Russian Science Foundation 20-15-00368
6 · The paper itself

Abstract

A decrease in the miR-124 expression was observed in various epithelial cancers. Like a classical suppressor, miR-124 can inhibit the translation of multiple oncogenic proteins. Epigenetic mechanisms play a significant role in the regulation of miR-124 expression and involve hypermethylation of the

Indexed as

Bone NeoplasmsLung NeoplasmsMicroRNAsOsteosarcomaRNA, Long NoncodingCell ProliferationEndonucleasesGene Expression Regulation, NeoplasticHumansPhosphatidylinositol 3-KinasesRNA, CircularEndonucleasesMicroRNAsMIRN124 microRNA, humanPhosphatidylinositol 3-KinasesRNA, CircularRNA, Long NoncodingSND1 protein, humanchemoresistancecircRNAEMTepigenetic mechanismsepithelial cancerslncRNAmetastasismiR-124signaling pathways

Identifiers

PMID36362406
PMCPMC9655303
OpenAlexW4308581106

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.