Evidence map›Paper›PMID 36362404›Full record

ArticleInternational journal of molecular sciences2022

On the Bioactivity of

Sara F Vieira, Virgínia M F Gonçalves, Carmen P Llaguno, Felipe Macías, Maria Elizabeth Tiritan, Rui L Reis, Helena Ferreira, Nuno M Neves

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Effect ofVeterinary and animal science · 2026
    Article
  2. Review
  3. Review
  4. Article
  5. Effects ofMolecules (Basel, Switzerland) · 2025
    Article
  6. Review
  7. Plants (Basel, Switzerland) · 2024
    Article
  8. Article
  9. Review
  10. Antioxidant and Anti-Inflammatory Activities ofLife (Basel, Switzerland) · 2023
    Article
  11. Antioxidants (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Sara F Vieira3B's Research Group, I3Bs-Research Institute on Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, AvePark, Parque de Ciência e Tecnologia, Zona Industrial da Gandra, Barco, 4805-017 Guimarães, Portugal.ORCID 0000-0001-9158-3114
Virgínia M F GonçalvesTOXRUN-Toxicology Research Unit, University Institute of Health Sciences (IUCS), CESPU, CRL, 4585-116 Gandra, Portugal.ORCID 0000-0002-9151-516X
Carmen P LlagunoDepartamento de Edafoloxía e Química Agrícola, Facultade de Bioloxía, Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain.
Felipe MacíasDepartamento de Edafoloxía e Química Agrícola, Facultade de Bioloxía, Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain.
Maria Elizabeth TiritanTOXRUN-Toxicology Research Unit, University Institute of Health Sciences (IUCS), CESPU, CRL, 4585-116 Gandra, Portugal.ORCID 0000-0003-3320-730X
Rui L Reis3B's Research Group, I3Bs-Research Institute on Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, AvePark, Parque de Ciência e Tecnologia, Zona Industrial da Gandra, Barco, 4805-017 Guimarães, Portugal.ORCID 0000-0002-4295-6129
Helena Ferreira3B's Research Group, I3Bs-Research Institute on Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, AvePark, Parque de Ciência e Tecnologia, Zona Industrial da Gandra, Barco, 4805-017 Guimarães, Portugal.ORCID 0000-0002-3770-9393
Nuno M Neves3B's Research Group, I3Bs-Research Institute on Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, AvePark, Parque de Ciência e Tecnologia, Zona Industrial da Gandra, Barco, 4805-017 Guimarães, Portugal.ORCID 0000-0003-3041-0687
University of Minho · PTUniversidade de Santiago de Compostela · ESCooperativa de Ensino Superior Politécnico e Universitário · PTUniversidade do Porto · PT

Funding

Cells4_IDs PTDC/BTM-SAL/28882/2017FROnTHERA NORTE-01-0145-FEDER-000023Fundação para a Ciência e Tecnologia COVID/BD/152012/2021Fundação para a Ciência e Tecnologia PD/BD/135246/2017Fundação para a Ciência e Tecnologia UIDB/04423/2020Fundação para a Ciência e Tecnologia UIDP/04423/2020NORTE 2020 Structured Project, co-funded by Norte2020 NORTE-01-0145-FEDER-000021PATH PD/00169/2013
6 · The paper itself

Abstract

Inflammatory diseases are the focus of several clinical studies, due to limitations and serious side effects of available therapies. Plant-based drugs (e.g., salicylic acid, morphine) have become landmarks in the pharmaceutical field. Therefore, we investigated the immunomodulatory effects of flowers, leaves, and roots from

Indexed as

Biological ProductsEchinaceaAdjuvants, ImmunologicAnti-Inflammatory AgentsInflammation MediatorsPlant ExtractsReactive Oxygen SpeciesSalicylic AcidTumor Necrosis Factor-alphaAdjuvants, ImmunologicAnti-Inflammatory AgentsBiological ProductsEchinacea extractInflammation MediatorsPlant ExtractsReactive Oxygen SpeciesSalicylic AcidTumor Necrosis Factor-alphaalkylamidesEchinacea purpurea extractsinflammationmacrophagesphenols/acidspro-inflammatory cytokinesreactive oxygen and nitrogen species

Identifiers

PMID36362404
PMCPMC9659013
OpenAlexW4308522284

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.