Evidence map›Paper›PMID 36362399›Full record

ArticleInternational journal of molecular sciences2022

Phytochemical and Antioxidant Profile of the Medicinal Plant

Maria Celeste Dias, Diana C G A Pinto, Maria Costa, Márcia Araújo, Conceição Santos, Artur M S Silva

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Anti-Inflammatory Effect of 21Food science & nutrition · 2025
    Article
  5. First Report ofPlants (Basel, Switzerland) · 2025
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Maria Celeste DiasCentre for Functional Ecology, Department of Life Sciences, University of Coimbra, Calçada Martim de Freitas, 3000-456 Coimbra, Portugal.ORCID 0000-0002-3083-6218
Diana C G A PintoLAQV/REQUIMTE, Department of Chemistry, Campus Universitário de Santiago, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0003-4249-7089
Maria CostaLAQV/REQUIMTE, Department of Chemistry, Campus Universitário de Santiago, University of Aveiro, 3810-193 Aveiro, Portugal.
Márcia AraújoCentre for Functional Ecology, Department of Life Sciences, University of Coimbra, Calçada Martim de Freitas, 3000-456 Coimbra, Portugal.ORCID 0000-0001-5440-1772
Conceição SantosIB2 Lab, Department of Biology & LAQV/REQUIMTE, Faculty of Sciences, Rua do Campo, Alegre, University of Porto, 4169-007 Porto, Portugal.ORCID 0000-0003-4129-6381
Artur M S SilvaLAQV/REQUIMTE, Department of Chemistry, Campus Universitário de Santiago, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0003-2861-8286

Funding

Fundação para a Ciência e Tecnologia SFRH/BD/116801/2016Fundação para a Ciência e Tecnologia SFRH/BPD/100865/2014
6 · The paper itself

Abstract

Environmental stress triggered by climate change can alter the plant’s metabolite profile, which affects its physiology and performance. This is particularly important in medicinal species because their economic value depends on the richness of their phytocompounds. We aimed to characterize how water deficit modulated the medicinal species Melia azedarach’s lipophilic profile and antioxidant status. Young plants were exposed to water deficit for 20 days, and lipophilic metabolite profile and the antioxidant capacity were evaluated. Leaves of M. azedarach are rich in important fatty acids and oleamide. Water deficit increased the radical scavenging capacity, total phenol, flavonoids, and catechol pools, and the accumulation of β-sitosterol, myo-inositol, succinic acid, sucrose, d-glucose and derivatives, d-psicofuranose, d-(+)-fructofuranose, and the fatty acids stearic, α-linolenic, linoleic and palmitic acids. These responses are relevant to protecting the plant against climate change-related stress and also increase the nutritional and antioxidant quality of M. azedarach leaves.

Indexed as

Melia azedarachPlants, MedicinalAntioxidantsFatty AcidsPhytochemicalsPlant ExtractsPlant LeavesWaterAntioxidantsFatty AcidsPhytochemicalsPlant ExtractsWatercatecholsdroughtflavonoidsMelia azedaracholeamidewater deficit

Identifiers

PMID36362399
PMCPMC9656347

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.