Evidence map›Paper›PMID 36362381›Full record

ArticleInternational journal of molecular sciences2022

In Vitro and In Vivo Biological Activity of Ruthenium 1,10-Phenanthroline-5,6-dione Arene Complexes.

Oscar A Lenis-Rojas, Catarina Roma-Rodrigues, Beatriz Carvalho, Pablo Cabezas-Sainz, Sabela Fernández Vila, Laura Sánchez, Pedro V Baptista, Alexandra R Fernandes, Beatriz Royo

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

  1. Inhibition and disruption of bacterial biofilms by a bipyridine-ruthenium complex: a broad-spectrum in vitro study.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026
    Article
  2. Article
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  6. Zebrafish as an Experimental Model for Human Disease.International journal of molecular sciences · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Oscar A Lenis-RojasITQB NOVA, Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Av. da República, 2780-157 Oeiras, Portugal.
Catarina Roma-RodriguesAssociate Laboratory i4HB-Institute for Health and Bioeconomy, NOVA School of Science and Technology, NOVA University Lisbon, 2819-516 Caparica, Portugal.ORCID 0000-0002-8676-6562
Beatriz CarvalhoAssociate Laboratory i4HB-Institute for Health and Bioeconomy, NOVA School of Science and Technology, NOVA University Lisbon, 2819-516 Caparica, Portugal.
Pablo Cabezas-SainzDepartamento de Zoología Genética y Antropología Física, Facultad de Veterinaria, Universidad de Santiago de Compostela, Campus de Lugo, 27002 Lugo, Spain.ORCID 0000-0002-7158-4459
Sabela Fernández VilaDepartamento de Zoología Genética y Antropología Física, Facultad de Veterinaria, Universidad de Santiago de Compostela, Campus de Lugo, 27002 Lugo, Spain.
Laura SánchezDepartamento de Zoología Genética y Antropología Física, Facultad de Veterinaria, Universidad de Santiago de Compostela, Campus de Lugo, 27002 Lugo, Spain.ORCID 0000-0001-7927-5303
Pedro V BaptistaAssociate Laboratory i4HB-Institute for Health and Bioeconomy, NOVA School of Science and Technology, NOVA University Lisbon, 2819-516 Caparica, Portugal.ORCID 0000-0001-5255-7095
Alexandra R FernandesAssociate Laboratory i4HB-Institute for Health and Bioeconomy, NOVA School of Science and Technology, NOVA University Lisbon, 2819-516 Caparica, Portugal.ORCID 0000-0003-2054-4438
Beatriz RoyoITQB NOVA, Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Av. da República, 2780-157 Oeiras, Portugal.ORCID 0000-0002-7909-9992
Unidade em Ciências Biomoleculares AplicadasUniversidade de Santiago de Compostela · ESUniversidade Nova de Lisboa · PT

Funding

Fundação para a Ciência e Tecnologia UIDB/04612/2020; UIDP/04612/2020; UIDP/04378/2020; UIDB/04378/2020; LA/P/0087/2020; LA/P/0140/2020NMR Network grant nº 022162POPH-Programa Operacional Potencial Humano, and FSE (European Social Fund) CEEC 2017 Initiative
6 · The paper itself

Abstract

Ruthenium(II) arene complexes exhibit promising chemotherapeutic properties. In this study, the effect of the counter anion in Ru(II) complexes was evaluated by analyzing the biological effect of two Ru(II)

Indexed as

Antineoplastic AgentsCoordination ComplexesOvarian NeoplasmsRutheniumAnimalsCell Line, TumorCell ProliferationFemaleHumansPhenanthrolinesZebrafish1,10-phenanthroline-5,6-dioneAntineoplastic AgentsCoordination ComplexesPhenanthrolinesRutheniumanticancer activityautophagyROSRu-dione complexeszebrafish

Identifiers

PMID36362381
PMCPMC9656482
OpenAlexW4308579504

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.